Table 7.
The error rate of misclassification of disease-causing and neutral variations using the SIFT score, normalized site entropy and change in residue frequency individually as predictors in the logistic regression analysis
| Dataset | SIFT score (%) | Normalized site entropy (%) | Change in residue frequency (%) | Combining all three features (%) |
|---|---|---|---|---|
| All variations | 18.41 | 18.60 | 19.92 | 11.95 |
| TM only | 11.07 | 19.37 | 19.37 | 10.67 |
| Non-TM only | 21.90 | 19.71 | 20.07 | 14.23 |