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. 2023 Nov 24;42:e2023001. doi: 10.1590/1984-0462/2024/42/2023001

Table 3. Analysis of potential maternal factors associated with the nutritional composition of human milk, 2018–2020.

n Lipids p-value Carbohydrates p-value Proteins p-value Calories p-value
Median (percentiles 25–75) Median (percentiles 25–75) Median (percentiles 25–75) Median (percentiles 25–75)
Alcohol during pregnancy No 155 2.4 (1.6–3.4) 0.862 7.7 (7.1–7.9) 0.842 0.8 (0.8–1.0) 0.730 57.0 (50.0–66.0) 0.762
Yes 26 2.7 (1.3–3.6) 7.8 (7.2–7.8) 0.8 (0.8–1.0) 58.5 (48.0–69.0)
Alcohol during breastfeeding No 160 2.5 (1.6–3.5) 0.969 7.7 (7.1–7.9) 0.533 0.8 (0.8–1.0) 0.379 57.0 (50.0–66.5) 0.950
Yes 21 2.6 (1.3–3.4) 7.8 (7.3–7.9) 0.8 (0.8–0.9) 59.0 (49.0–67.0)
Smoking during pregnancy No 177 2.5 (1.6–3.4) 0.284 7.7 (7.2–7.9) 0.739 0.8 (0.8–1.0) 0.563 57.0 (50.0–67.0) 0.453
Yes 4 3.4 (2.4–5.4) 7.2 (6.4–8.8) 0.9 (0.8–2.6) 61.0 (54.5–96.0)
Smoking during breastfeeding No 180 2.5 (1.6–3.4) 7.7 (7.2–7.9) 0.8 (0.8–1.0) 57.0 (49.5–66.5)
Yes 1 7.4 9.7 4.1 130.0
Pre-gestational hypertension No 178 2.5 (1.6–3.5) 0.998 7.7 (7.2–7.9) 0.475 0.8 (0.8–1.0) 0.722 57.0 (49.0–67.0) 0.907
Yes 3 2.5 (2.2–2.8) 7.9 (7.0–8.1) 0.8 (0.7–1.0) 59.0 (52.0–64.0)
Hypertension during pregnancy No 168 2.5 (1.6–3.5) 0.663 7.7 (7.2–7.9) 0.648 0.8 (0.8–1.0) 0.981 57.0 (50.0–67.0) 0.703
Yes 13 2.5 (1.7–3.0) 7.6 (7.2–8.0) 0.8 (0.8–1.0) 59.0 (49.0–65.0)
Pre-gestational diabetes mellitus No 181 2.5 (1.6–3.4) 7.7 (7.2–7.9) 0.8 (0.8–1.0) 57.0 (50.0–67.0)
Yes 0
Diabetes mellitus during pregnancy No 175 2.5 (1.6–3.5) 0.622 7.7 (7.1–7.9) 0.805 0.8 (0.8–1.0) 0.779 57.0 (49.0–67.0) 0.692
Yes 6 3.1 (1.7–3.3) 7.7 (7.2–7.9) 0.9 (0.8–0.9) 62.0 (51.0–66.0)
Gestational age (weeks) ≥37 172 2.5 (1.6–3.5) 0.371 7.7 (7.2–7.9) 0.593 0.8 (0.8–1.0) 0.398 57.0 (49.5–67.0) 0.396
34–36.9 8 2.9 (1.9–3.7) 7.6 (7.2–7.7) 1.0 (0.7–1.0) 60.5 (53.5–65.5)
<34 1 1.1 7.4 0.7 44.0
Sex of the newborn Female 98 2.5 (1.6–3.4) 0.606 7.7 (7.1–7.9) 0.858 0.8 (0.8–1.0) 0.996 56.5 (49.0–67.0) 0.521
Male 83 2.5 (1.6–3.7) 7.7 (7.2–7.9) 0.8 (0.8–0.9) 58.0 (51.0–68.0)