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. 2023 Dec 1;13(50):35127–35136. doi: 10.1039/d3ra06537e

The astaxanthin/kaempferol co-encapsulated nanoparticles inhibit NO in LPS stimulated RAW264.7 cells.

Inhibition of NO production (%) Inhibition of NO production (%)
Concentration (μg mL−1) AK1 AK3 Concentration (μg mL−1) L-NMMA
0.08 0.66 ± 0.70 22.65 ± 1.05 0.8 9.57 ± 0.29
0.4 5.60 ± 1.40 58.98 ± 1.40 4 24.36 ± 0.72
2 12.03 ± 1.40 82.13 ± 0.70 20 80.73 ± 1.86
10 46.62 ± 2.09 89.88 ± 1.75 100 99.39 ± 2.59
IC50 (μg mL−1) >10 3.44 ± 0.23 IC50 (μg mL−1) 7.92 ± 0.79