|
XKS1
|
Scheffersomyces stipitis XYL1, XYL2
|
Fermentation at high xylose concentrations and reduced xylitol production |
(Ho, Chen & Brainard, 1998) |
|
Scheffersomyces stipitis XYL1, XYL2 and XYL3 / pho13Δ |
Overexpression of XK genes (XYL3 or XKS1) increases the rate of xylose assimilation and maintain ATP levels inside cells |
(Kim et al., 2013) |
| LSK1 - xylulokinase mutant |
Increased enzyme activity improved xylulose conversion and accelerated ethanol production by 30–130% |
(Deng & Ho, 1990) |
|
Scheffersomyces stipitis XYL1, XYL2
|
Deleterious effect associated with uncontrolled overexpression of XKS1 / xylulose-5-phosphate accumulation and ATP depletion |
(Johansson et al., 2001) |
| FY1679 (ura3- 52/ura3-52; his3v200/his3; leu2v1/leu2; trp1v63/ trp1; gal2/gal2)
|
High levels of expression of this gene have a deleterious effect |
(Rodriguez-Peña et al., 1998) |
|
XKS1 / Scheffersomyces stipitis XYL3
|
Scheffersomyces stipitis XYL1, XYL2
|
Growth inhibition on xylose / expression levels should consider the metabolic capacity of the strain |
(Jin et al., 2003) |
|
RPE1 / RKI1 / TAL1 / TKL1
|
Piromyces sp. E2 XYLA / gre3Δ |
Specific xylose consumption rate of 1.1 g g−1 h−1
|
(Kuyper et al., 2005) |
|
Scheffersomyces stipitis XYL1 and XYL2 / XKS1 / gre3Δ |
Increased rate of xylose consumption |
(Karhumaa et al., 2007a) |
|
TAL1
|
Scheffersomyces stipitis XYL1, XYL2 and XYL3 / gre3Δ |
Improvement in xylose assimilation |
(Ni, Laplaza & Jeffries, 2007) |
|
TAL1 / TKL1
|
Scheffersomyces stipitis XYL1 and XYL2 / XKS1
|
Important role in xylose consumption and fermentation |
(Matsushika et al., 2012) |
|
XKS1 / TAL1/ TKL1 / SOL3 / GND1
|
Scheffersomyces stipitis XYL1 and XYL2 / XKS1
|
Increased consumption of xylose by 31% |
(Wahlbom et al., 2003) |
|
GND1 / SOL3 / TAL1 / RKI1 / TKL1
|
Orpinomyces sp. XYLA / XKS1 / gre3Δ/ pho13Δ |
Improves xylose consumption rate |
(Bamba, Hasunuma & Kondo, 2016) |
|
SOL3 / TAL1
|
Scheffersomyces stipitis XYL1 and XYL2 / XKS1
|
Fastest growth on xylose by 19% (SOL3) and 24% (TAL1) |
(Bengtsson et al., 2008) |
|
RPE1
|
Piromyces sp. XYLA *3 / pho13Δ / gre3Δ/ asc1Δ |
Significantly improved xylose utilization |
(Hoang Nguyen Tran et al., 2020) |
|
NRM1/YHP1
|
Ru-XYLA / XKS1 / RKI1 / RPE1 / TKL1 / TKL2 / TAL1 / cox4Δ/ gre3Δ |
NRM1 increased the xylose utilization rate by 30%. YHP1 increased the volumetric xylose utilization rate by 5.6% |
(Wei et al., 2018) |
|
STT4 / RGI2 / TFC3
|
Ru-XYLA / XKS1 / RKI1 / RPE1 / TKL1 / TKL2 / TAL1 / cox4Δ/gre3Δ |
Increased xylose specific utilization rates: STT4 (36.9%), RGI2 (29.7%) and TFC3 (42.8%) |
(Wei et al., 2019) |
|
Piromyces sp. E2 XYLA
|
Scheffersomyces stipitis XYL3 and TAL1 / RPE1 / RKI1 / TKL1
|
Xylose consumption rate of 1.866 g g−1 h−1
|
(Zhou et al., 2012) |
|
XYL2
|
Scheffersomyces stipitis XYL1 and XYL3
|
Increased ethanol yields and decrease in xylitol production |
(Kim et al., 2012) |
