FIGURE 4.

For a simulation in which deposition happens only on the right leaflet, snapshots during (A) middle of diastole, (B) peak systole, (C), end systole, and (D) middle of diastole the last cycle showing (top) the normalized fluid-phase concentration $c_{\mathrm{f}}/c_{\mathrm{f}}^{\mathrm{m}\mathrm{a}\mathrm{x}}$ and surface concentration $C_{\mathrm{b}}{J}_{\mathrm{s}}/C_{\mathrm{b}}^{\mathrm{m}\mathrm{a}\mathrm{x}}$ and (bottom) the fluid velocity magnitude. This simulation uses $\beta =600$. Notice that the right leaflet is considerably stiffer than the left one and that the fluid concentration $c_{\mathrm{f}}$ is depleted in and downstream of the aortic sinus. See supplementary movie S1