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. 2023 Oct;33(10):1848–1864. doi: 10.1101/gr.277947.123

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© 2023 Yuan et al.; Published by Cold Spring Harbor Laboratory Press

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Figure 4. — Open chromatin regions are enriched in cis-regulatory variants. Enrichment of variants mapping to NMF component-specific ATAC-seq peaks in credible sets (r² ≥ 0.9 with the lead variant) of 3857 blood-specific and 2212 liver-specific cis eQTL, evaluated by following the method of Trynka et al. (2015). The x-axis shows statistical significance (log(1/p)) of the enrichment; y-axis, NMF component. Green indicates proximal peaks; red, distal peaks. (A) Blood-specific eQTLs. (B) Liver-specific eQTLs.