Table III.
Per-patient comparison of prepubertal and pubertal growth rates with longitudinal growth rate of target PN in puberty cohort in milliliters per month and percent change from baseline per month (n = 14*)
| Per-patient longitudinal absolute rates of growth (mL/month) | Absolute rate prepuberty (mL/month) | Absolute rate pubertal (mL/month) | Longitudinal percent change from baseline (%/month) | Percent change prepuberty (%/month) | Percent change pubertal (%/month) |
|---|---|---|---|---|---|
|
| |||||
| 3.68 | 3.83 | 3.5 | 1.45 | 1.23 | 0.78 |
| 0.015 | −0.0042 | −0.03 | 0.282 | −0.09 | 0.69 |
| 1.59 | 1.84 | 2.76 | 1.49 | 1.4 | 1.53 |
| 2.5 | 3.28 | 1.8 | 1.06 | 1.15 | 0.624 |
| 0.204 | 0.13 | 0.23 | 1.21 | 0.654 | 0.9 |
| 0.44 | 1.13 | 0.39 | 0.31 | 0.825 | 0.198 |
| 1.85 | 1.49 | 2.7 | 2.62 | 1.16 | 1.47 |
| 1.63 | 1.78 | 1.73 | 4.4 | 1.44 | 0.91 |
| 0.002 | −0.006 | −0.031 | 0.0011 | −0.06 | −0.12 |
| 0.298 | 0.38 | 0.35 | 8.75 | 11.1 | 2.9 |
| 0.069 | 0.13 | 0.06 | 1.21 | 2.3 | 0.58 |
| 0.37 | 0.29 | 0.24 | 0.367 | 0.223 | 0.154 |
| 0.0225 | 0.023 | 0.02 | 0.568 | 0.51 | 0.147 |
| 0.0765 | 0.12 | 0.025 | 2.37 | 3.48 | 0.61 |
| Proportion of patients with growth rate above the longitudinal rate | 71% | 36% | Proportion of patients with percent change above the longitudinal rate | 36% | 14% |
One patient was excluded from longitudinal analysis owing to tumor debulking.