Table 2.
Correlations of E47 gene expression with clinical parameters.
| Group | Age (year) | BMI (kg/m2) | Body fat (%) | WHR | LDDST (µg/l) | UFC (µg/24h) | LNSC (µg/l) | Hb1c (%) | HOMA- IR | TG (mg/dl) | Total cholesterol (mg/dl) | HDL (mg/dl) | LDL (mg/dl) | RR-sys (mmHg) | RR-dia (mmHg) | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Overt CS | E47 | ρ | .058 | -.083 | -.033 | .090 | -.053 | .082 | -.069 | .179 | .089 | -.120 | -.208 | .060 | -.137 | .112 | -.123 |
| P | .764 | .674 | .915 | .685 | .796 | .685 | .728 | .362 | .658 | .550 | .297 | .767 | .494 | .570 | .531 | ||
| N | 29 | 28 | 13 | 23 | 26 | 27 | 28 | 28 | 27 | 27 | 27 | 27 | 27 | 28 | 28 | ||
| Remission | E47 | ρ | -.031 | -.014 | .044 | -.188 | .095 | -.136 | .001 | -.055 | -.063 | -.105 | -.306" | -.052 | -.257 | -.016 | -.119 |
| P | .769 | .894 | .766 | .079 | .625 | .255 | .992 | .604 | .563 | .324 | .003 | .624 | .015 | .883 | .271 | ||
| N | 90 | 89 | 48 | 88 | 29 | 72 | 67 | 90 | 86 | 90 | 90 | 90 | 90 | 87 | 87 | ||
| Controls | E47 | ρ | .027 | .141 | -.077 | -.042 | .121 | .267 | -.181 | -274 | .157 | .024 | -.094 | .163 | -.172 | .246 | .328 |
| p | .897 | .502 | .785 | .846 | .583 | .196 | .386 | .186 | .465 | .910 | .662 | .446 | .443 | .236 | .110 | ||
| N | 26 | 25 | 15 | 24 | 23 | 25 | 25 | 25 | 24 | 24 | 24 | 24 | 22 | 25 | 25 |
ρ: Spearman’s rank correlation coefficient; CS: Cushing’s syndrome; WHR: waist-to-hip ratio; LDDST: low-dose dexamethasone suppression test; UFC: urinary free cortisol; LNSC: late-night salivary cortisol; HOMA-IR: Homeostasis Model Assessment of Insulin Resistance; TG: triglycerides; RR-sys: systolic blood pressure; RR-dia: diastolic blood pressure.