Table 4.

Adjusted hazard ratios comparing all-cause mortality for patients with tonsillar cancer according to total expression of differentially expressed proteins between CD8 AOIs outside (i.e., stroma) and inside cancer-cell islets (adjusted p.value < 0.05, FC > 1.5) (n=95) in CD8⁺ regions.

	Univariable models		Multivariable model 1 (Table 2)
	HR (95% CI)	P	HR (95% CI)	P
Fibronectin	1.000 (0.996 - 1.004)	0.090	–	–
CD4	0.999 (0.999 - 1.000)	0.576	–	–
CD27	0.999 (0.996 - 1.002)	0.451	–	–
SMA	0.999 (0.998 - 1.000)	0.103	–	–
4-1BB	0.996 (0.989 - 1.003)	0.263	–	–
Ki-67	0.999 (0.999 - 1.000)	0.387	–	–
PD-L2	0.988 (0.974 – 1.002)	0.097	0.987 (0.975 – 1.000)	0.055
STING	0.999 (0.999 – 1.000)	0.274	–	–
PD-L1	0.994 (0.988 - 0.999)	0.040	0.996 (0.991 – 1.002)	0.219

Significant markers are indicated in bold.