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. 2023 Nov 17;13:1193574. doi: 10.3389/fonc.2023.1193574

Table 1.

Analysis of clinicopathological factors affecting the outcome by meta regression.

Variable Moderators d.f. Qm p-value Variable Moderators d.f. Qm p-value
1-year local control Age 1(27) 0.01 0.926 1-year overall survival Age 1(28) 0.85 0.356
Male 1(25) 0.68 0.409 Male 1(26) 0.50 0.479
Right adrenal 1(21) 0.74 0.391 Right adrenal 1(22) 0.00 0.969
  Bilateral 1(27) 2.01 0.156   Bilateral 1(28) 0.05 0.823
Concurrent therapy 1(8) 2.53 0.112 Concurrent therapy 1(11) 0.01 0.905
SCLC 1(20) 4.37 0.037 SCLC 1(20) 2.40 0.121
Melanoma 1(24) 0.07 0.791 Melanoma 1(24) 1.31 0.253
Solitary 1(16) 2.94 0.087 Solitary 1(17) 0.42 0.519
Synchronous 1(15) 1.52 0.218 Synchronous 1(15) 0.21 0.650
Prescribed dose 1(26) 1.20 0.273 Prescribed dose 1(27) 0.11 0.741
Fractions 1(25) 1.41 0.236 Fractions 1(26) 1.80 0.180
Dose per fraction 1(26) 15.10 <.001 Dose per fraction 1(27) 3.10 0.078
BED10 1(27) 23.89 <.001 BED10 1(28) 1.95 0.163
PTV 1(18) 2.89 0.089 PTV 1(18) 0.15 0.703
GTV 1(25) 0.72 0.396 GTV 1(26) 1.98 0.160
Tumor size 1(7) 0.03 0.861 Tumor size 1(7) 0.52 0.473
Tracking technology 1(25) 3.31 0.069 Tracking technology 1(26) 5.73 0.017
2-year local control Age 1(24) 0.17 0.684 2-year overall survival Age 1(27) 2.40 0.121
Male 1(22) 0.48 0.490 Male 1(25) 0.02 0.895
Right adrenal 1(18) 0.51 0.473 Right adrenal 1(21) 0.39 0.534
  Bilateral 1(24) 1.02 0.313   Bilateral 1(27) 1.33 0.249
Concurrent therapy 1(8) 0.09 0.761 Concurrent therapy 1(11) 1.65 0.199
SCLC 1(17) 0.03 0.871 SCLC 1(19) 10.04 0.002
Melanoma 1(21) 1.03 0.310 Melanoma 1(23) 0.03 0.863
Solitary 1(15) 1.85 0.174 Solitary 1(17) 0.68 0.409
Synchronous 1(13) 0.32 0.570 Synchronous 1(15) 1.69 0.194
Prescribed dose 1(23) 0.82 0.365 Prescribed dose 1(26) 0.10 0.755
Fractions 1(22) 0.23 0.629 Fractions 1(25) 3.21 0.073
Dose per fraction 1(23) 1.35 0.245 Dose per fraction 1(26) 6.60 0.010
BED10 1(24) 7.72 0.006 BED10 1(27) 2.82 0.093
PTV 1(16) 0.47 0.491 PTV 1(17) 4.87 0.027
GTV 1(24) 0.13 0.718 GTV 1(26) 8.20 0.004
Tumor size 1(6) 1.42 0.233 Tumor size 1(7) 1.27 0.261
Tracking technology 1(22) 0.34 0.559 Tracking technology 1(25) 8.75 0.003

SCLC, small cell lung cancer; PTV, planning target volume; GTV, gross tumor volume. The red shading mean that significantly difference (p <0.05).