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. 2023 Nov 30;82(6):458–469. doi: 10.1097/FJC.0000000000001484

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Copyright © 2023 The Author(s). Published by Wolters Kluwer Health, Inc.

This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.

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FIGURE 6. — Cell and animal studies on TCF3-mediated M2 polarization and inhibition of MMP secretion by macrophages through miR-143-5p/CCL20. A, Western blot analysis of MMP9 and MMP2 in macrophages. B, Western blot analysis of M1 macrophage and M2 markers. C, Flow cytometric analysis of CD11b and CD163. D, Apparent view of AAAs in mice. E, The expression of TCF3 and CCL20 was detected by immunohistochemical staining. F, HE staining of mouse abdominal aortas. G, EVG staining of mouse abdominal aortas. H, ELISA analysis of the expression of inflammatory factors in mice. The uncropped original western blot images are shown in Supplemental Digital Content 1 (see File 1, http://links.lww.com/JCVP/A991). oe-TCF3 versus NC, oe-TCF3+ miR-143-5p mimic versus oe-TCF3, oe-TCF3+ miR-143-5p mimic+oe-CCL20 versus oe-TCF3+ miR-143-5p mimic, *P < 0.05, **P < 0.01, ***P < 0.001.