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. 2023 Apr 19;3:1166174. doi: 10.3389/fepid.2023.1166174

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© 2023 Herrin, Sherris, Dearborn, Loftus, Szpiro, Moore, Adgent, Barrett, Nguyen, Carroll and Karr.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Assessment of effect modification by child sex. Relative risks (95% confidence intervals) are shown for overall, male- and female-specific associations between prenatal exposure to cleaning chemicals and development of current wheeze (A) and current asthma (B) at age 4–6 years. Models were adjusted for child age, study site, maternal race, maternal ethnicity, education at enrollment, maternal history of asthma, maternal age at delivery, maternal self-report of smoking status at enrollment, household size category, region-and inflation-adjusted household income, postnatal second-hand smoke exposure, season of birth, firstborn status, child sex, and a multiplicative interaction term for exposure to cleaning chemicals by child sex.