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. 2023 Aug 3;12:e79548. doi: 10.7554/eLife.79548

Appendix 2—table 18. “Bone-Rx” Cohort (Region=Northeast), Patient Characteristics Pre/Post Match.

"Bone-Rx" Cohort / Region=Northeast Unmatched "Bone-Rx" Cohort / Region=Northeast Matched
All BP Non-user BP User p-value All BP Non-user BP User p-value
N % N % N % N % N % N %
All Patients 135,867 100.0% 16,139 11.9% 119,728 88.1% 31,986 100.0% 15,993 50.0% 15,993 50.0%
Age
≤20 245 0.2% ≤10 0.1% 236 0.2% <0.001 15 0.0% ≤10 0.1% ≤10 0.0% 0.99
21-40 891 0.7% 127 0.8% 764 0.6% 250 0.8% 124 0.8% 126 0.8%
41-50 2,340 1.7% 298 1.8% 2,042 1.7% 570 1.8% 290 1.8% 280 1.8%
51-60 20,069 14.8% 2,059 12.8% 18,010 15.0% 4,088 12.8% 2,049 12.8% 2,039 12.7%
61-70 45,896 33.8% 4,802 29.8% 41,094 34.3% 9,526 29.8% 4,767 29.8% 4,759 29.8%
71-80 42,828 31.5% 5,267 32.6% 37,561 31.4% 10,465 32.7% 5,226 32.7% 5,239 32.8%
≥81 23,598 17.4% 3,577 22.2% 20,021 16.7% 7,072 22.1% 3,528 22.1% 3,544 22.2%
Gender
Female 122,485 90.2% 14,115 87.5% 108,370 90.5% <0.001 28,157 88.0% 14,062 87.9% 14,095 88.1% 0.57
Male 13,382 9.8% 2,024 12.5% 11,358 9.5% 3,829 12.0% 1,931 12.1% 1,898 11.9%
Insurance
Commercial 37,810 27.8% 4,517 28.0% 33,293 27.8% <0.001 8,927 27.9% 4,459 27.9% 4,468 27.9% 0.99
Dual 8,434 6.2% 829 5.1% 7,605 6.4% 1,637 5.1% 824 5.2% 813 5.1%
Medicaid 25,296 18.6% 2,082 12.9% 23,214 19.4% 4,122 12.9% 2,067 12.9% 2,055 12.8%
Medicare 64,327 47.3% 8,711 54.0% 55,616 46.5% 17,300 54.1% 8,643 54.0% 8,657 54.1%
PCP Visit 2019
No 56,593 41.7% 6,726 41.7% 49,867 41.7% 0.95 13,307 41.6% 6,654 41.6% 6,653 41.6% 0.99
Yes 79,274 58.3% 9,413 58.3% 69,861 58.3% 18,679 58.4% 9,339 58.4% 9,340 58.4%
Continuous Outcomes
mean SD mean SD mean SD p-value mean SD mean SD mean SD p-value
CCI 1.06 1.89 1.97 2.70 0.93 1.71 <0.001 1.89 2.57 1.89 2.58 1.89 2.57 0.91

BP: bisphosphonate; CCI: Charlson Comorbidity Index; PCP: primary care physician; SD: standard deviation.