Appendix 2—table 23. “Osteo-Dx-Rx” Cohort, Patient Characteristics Pre/Post Match.
| "Osteo-Dx-Rx" Cohort / All Observations Unmatched | "Osteo-Dx-Rx" Cohort / All Observations Matched | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| All | BP Non-user | BP User | p-value | All | BP Non-user | BP User | p-value | |||||||
| N | % | N | % | N | % | N | % | N | % | N | % | |||
| All Patients | 60,043 | 100.0% | 8,392 | 14.0% | 51,651 | 86.0% | 15,898 | 100.0% | 7,949 | 50.0% | 7,949 | 50.0% | ||
| Age | ||||||||||||||
| 51-60 | 6,443 | 10.7% | 753 | 9.0% | 5,690 | 11.0% | <0.001 | 1,430 | 9.0% | 723 | 9.1% | 707 | 8.9% | 0.95 |
| 61-70 | 20,187 | 33.6% | 2,492 | 29.7% | 17,695 | 34.3% | 4,821 | 30.3% | 2,397 | 30.2% | 2,424 | 30.5% | ||
| 71-80 | 21,545 | 35.9% | 2,964 | 35.3% | 18,581 | 36.0% | 5,677 | 35.7% | 2,841 | 35.7% | 2,836 | 35.7% | ||
| ≥81 | 11,868 | 19.8% | 2,183 | 26.0% | 9,685 | 18.8% | 3,970 | 25.0% | 1,988 | 25.0% | 1,982 | 24.9% | ||
| State | ||||||||||||||
| CA | 24,489 | 40.8% | 2,558 | 30.5% | 21,931 | 42.5% | <0.001 | 4,886 | 30.7% | 2,443 | 30.7% | 2,443 | 30.7% | 1.00 |
| FL | 11,904 | 19.8% | 1,767 | 21.1% | 10,137 | 19.6% | 3,256 | 20.5% | 1,628 | 20.5% | 1,628 | 20.5% | ||
| IL | 4,447 | 7.4% | 678 | 8.1% | 3,769 | 7.3% | 1,168 | 7.3% | 584 | 7.3% | 584 | 7.3% | ||
| NY | 19,203 | 32.0% | 3,389 | 40.4% | 15,814 | 30.6% | 6,588 | 41.4% | 3,294 | 41.4% | 3,294 | 41.4% | ||
| Insurance | ||||||||||||||
| Commercial | 12,990 | 21.6% | 2,048 | 24.4% | 10,942 | 21.2% | <0.001 | 3,736 | 23.5% | 1,868 | 23.5% | 1,868 | 23.5% | 1.00 |
| Dual | 3,652 | 6.1% | 313 | 3.7% | 3,339 | 6.5% | 554 | 3.5% | 277 | 3.5% | 277 | 3.5% | ||
| Medicaid | 13,698 | 22.8% | 1,785 | 21.3% | 11,913 | 23.1% | 3,392 | 21.3% | 1,696 | 21.3% | 1,696 | 21.3% | ||
| Medicare | 29,703 | 49.5% | 4,246 | 50.6% | 25,457 | 49.3% | 8,216 | 51.7% | 4,108 | 51.7% | 4,108 | 51.7% | ||
| PCP Visit 2019 | ||||||||||||||
| No | 14,089 | 23.5% | 2,427 | 28.9% | 11,662 | 22.6% | <0.001 | 4,487 | 28.2% | 2,243 | 28.2% | 2,244 | 28.2% | 0.99 |
| Yes | 45,954 | 76.5% | 5,965 | 71.1% | 39,989 | 77.4% | 11,411 | 71.8% | 5,706 | 71.8% | 5,705 | 71.8% | ||
| Cancer Dx | ||||||||||||||
| No | 52,301 | 87.1% | 6,765 | 80.6% | 45,536 | 88.2% | <0.001 | 13,116 | 82.5% | 6,548 | 82.4% | 6,568 | 82.6% | 0.68 |
| Yes | 7,742 | 12.9% | 1,627 | 19.4% | 6,115 | 11.8% | 2,782 | 17.5% | 1,401 | 17.6% | 1,381 | 17.4% | ||
| COPD Dx | ||||||||||||||
| No | 53,446 | 89.0% | 7,035 | 83.8% | 46,411 | 89.9% | <0.001 | 13,705 | 86.2% | 6,834 | 86.0% | 6,871 | 86.4% | 0.39 |
| Yes | 6,597 | 11.0% | 1,357 | 16.2% | 5,240 | 10.1% | 2,193 | 13.8% | 1,115 | 14.0% | 1,078 | 13.6% | ||
| Heart Failure Dx | ||||||||||||||
| No | 56,005 | 93.3% | 7,492 | 89.3% | 48,513 | 93.9% | <0.001 | 14,475 | 91.0% | 7,218 | 90.8% | 7,257 | 91.3% | 0.28 |
| Yes | 4,038 | 6.7% | 900 | 10.7% | 3,138 | 6.1% | 1,423 | 9.0% | 731 | 9.2% | 692 | 8.7% | ||
| Hypertension Dx | ||||||||||||||
| No | 24,966 | 41.6% | 3,281 | 39.1% | 21,685 | 42.0% | <0.001 | 6,268 | 39.4% | 3,137 | 39.5% | 3,131 | 39.4% | 0.92 |
| Yes | 35,077 | 58.4% | 5,111 | 60.9% | 29,966 | 58.0% | 9,630 | 60.6% | 4,812 | 60.5% | 4,818 | 60.6% | ||
| Dyslipidemia Dx | ||||||||||||||
| No | 24,095 | 40.1% | 3,295 | 39.3% | 20,800 | 40.3% | 0.08 | 6,187 | 38.9% | 3,101 | 39.0% | 3,086 | 38.8% | 0.81 |
| Yes | 35,948 | 59.9% | 5,097 | 60.7% | 30,851 | 59.7% | 9,711 | 61.1% | 4,848 | 61.0% | 4,863 | 61.2% | ||
| Obesity Dx | ||||||||||||||
| No | 53,453 | 89.0% | 7,583 | 90.4% | 45,870 | 88.8% | <0.001 | 14,468 | 91.0% | 7,217 | 90.8% | 7,251 | 91.2% | 0.35 |
| Yes | 6,590 | 11.0% | 809 | 9.6% | 5,781 | 11.2% | 1,430 | 9.0% | 732 | 9.2% | 698 | 8.8% | ||
| Type 2 Diabetes Dx | ||||||||||||||
| No | 44,565 | 74.2% | 6,132 | 73.1% | 38,433 | 74.4% | 0.009 | 11,759 | 74.0% | 5,859 | 73.7% | 5,900 | 74.2% | 0.46 |
| Yes | 15,478 | 25.8% | 2,260 | 26.9% | 13,218 | 25.6% | 4,139 | 26.0% | 2,090 | 26.3% | 2,049 | 25.8% | ||
| Depression Dx | ||||||||||||||
| No | 51,609 | 86.0% | 7,114 | 84.8% | 44,495 | 86.1% | 0.001 | 13,697 | 86.2% | 6,844 | 86.1% | 6,853 | 86.2% | 0.84 |
| Yes | 8,434 | 14.0% | 1,278 | 15.2% | 7,156 | 13.9% | 2,201 | 13.8% | 1,105 | 13.9% | 1,096 | 13.8% | ||
BP: bisphosphonate; CCI: Charlson Comorbidity Index; CA: California; Dx: diagnosis; FL: Florida; IL: Illinois; NY: New York; PCP: primary care physician.