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. 2023 Aug 3;12:e79548. doi: 10.7554/eLife.79548

Appendix 2—table 26. Statin User Cohort (All Regions) by BP Use, Patient Characteristics Pre/Post Match of BP Users/Non-users.

All Statin Users by BP: Unmatched All Statin Users by BP: Matched
All BP Non-user BP User p-value All BP Non-user BP User p-value
N % N % N % N % N % N %
All Patients 1,436,300 100.0% 1,218,319 84.8% 217,981 15.2% 426,960 100.0% 213,480 50.0% 213,480 50.0%
Age
≤20 1,385 0.1% 1,365 0.1% 20 0.0% <0.001 42 0.0% 22 0.0% 20 0.0% 1.00
21-40 44,389 3.1% 44,042 3.6% 347 0.2% 704 0.2% 357 0.2% 347 0.2%
41-50 135,867 9.5% 133,850 11.0% 2,017 0.9% 4,033 0.9% 2,016 0.9% 2,017 0.9%
51-60 356,032 24.8% 333,325 27.4% 22,707 10.4% 45,439 10.6% 22,732 10.6% 22,707 10.6%
61-70 428,943 29.9% 356,208 29.2% 72,735 33.4% 144,861 33.9% 72,341 33.9% 72,520 34.0%
71-80 302,081 21.0% 223,651 18.4% 78,430 36.0% 150,527 35.3% 75,316 35.3% 75,211 35.2%
≥81 167,603 11.7% 125,878 10.3% 41,725 19.1% 81,354 19.1% 40,696 19.1% 40,658 19.0%
Gender
Female 843,147 58.7% 646,846 53.1% 196,301 90.1% <0.001 383,586 89.8% 191,786 89.8% 191,800 89.8% 0.94
Male 593,153 41.3% 571,473 46.9% 21,680 9.9% 43,374 10.2% 21,694 10.2% 21,680 10.2%
Region
Midwest 271,319 18.9% 237,718 19.5% 33,601 15.4% <0.001 67,050 15.7% 33,525 15.7% 33,525 15.7% 1.00
Northeast 423,934 29.5% 366,936 30.1% 56,998 26.1% 113,308 26.5% 56,654 26.5% 56,654 26.5%
South 523,112 36.4% 442,996 36.4% 80,116 36.8% 157,838 37.0% 78,919 37.0% 78,919 37.0%
West 217,935 15.2% 170,669 14.0% 47,266 21.7% 88,764 20.8% 44,382 20.8% 44,382 20.8%
Insurance
Commercial 587,625 40.9% 533,843 43.8% 53,782 24.7% <0.001 107,552 25.2% 53,774 25.2% 53,778 25.2% 1.00
Dual 55,356 3.9% 42,041 3.5% 13,315 6.1% 24,380 5.7% 12,183 5.7% 12,197 5.7%
Medicaid 320,911 22.3% 280,799 23.0% 40,112 18.4% 76,121 17.8% 38,050 17.8% 38,071 17.8%
Medicare 472,408 32.9% 361,636 29.7% 110,772 50.8% 218,907 51.3% 109,473 51.3% 109,434 51.3%
PCP Visit 2019
No 507,726 35.3% 430,446 35.3% 77,280 35.5% 0.27 151,395 35.5% 75,614 35.4% 75,781 35.5% 0.59
Yes 928,574 64.7% 787,873 64.7% 140,701 64.5% 275,565 64.5% 137,866 64.6% 137,699 64.5%
Continuous Outcomes
mean SD mean SD mean SD p-value mean SD mean SD mean SD p-value
CCI 1.11 1.75 1.13 1.77 0.95 1.66 <0.001 0.97 1.66 0.97 1.66 0.97 1.67 0.79

BP: bisphosphonate; CCI: Charlson Comorbidity Index; PCP: primary care physician; SD: standard deviation.