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. 2023 Aug 3;12:e79548. doi: 10.7554/eLife.79548

Appendix 2—table 28. Statin Non-user Cohort (All Regions) by BP Use, Patient Characteristics Pre/Post Match of BP Users/Non-users.

All Statin Non-users by BP Use: Unmatched All Statin Non-users by BP: Matched
All BP Non-users BP Users p-value All BP Non-users BP Users p-value
N % N % N % N % N % N %
All Patients 1,436,300 100.0% 1,311,457 91.3% 124,843 8.7% 249,432 100.0% 124,716 50.0% 124,716 50.0%
Age
≤20 1,387 0.1% 1,383 0.1% 4 0.0% <0.001 6 0.0% 2 0.0% 4 0.0% 0.99
21-40 44,371 3.1% 44,170 3.4% 201 0.2% 413 0.2% 212 0.2% 201 0.2%
41-50 135,748 9.5% 134,305 10.2% 1,443 1.2% 2,880 1.2% 1,437 1.2% 1,443 1.2%
51-60 354,449 24.7% 336,779 25.7% 17,670 14.2% 35,335 14.2% 17,665 14.2% 17,670 14.2%
61-70 428,326 29.8% 381,936 29.1% 46,390 37.2% 92,791 37.2% 46,401 37.2% 46,390 37.2%
71-80 303,279 21.1% 264,157 20.1% 39,122 31.3% 78,077 31.3% 39,037 31.3% 39,040 31.3%
≥81 168,740 11.7% 148,727 11.3% 20,013 16.0% 39,930 16.0% 19,962 16.0% 19,968 16.0%
Gender
Female 839,207 58.4% 727,324 55.5% 111,883 89.6% <0.001 223,501 89.6% 111,745 89.6% 111,756 89.6% 0.94
Male 597,093 41.6% 584,133 44.5% 12,960 10.4% 25,931 10.4% 12,971 10.4% 12,960 10.4%
Region
Midwest 271,319 18.9% 249,383 19.0% 21,936 17.6% <0.001 43,870 17.6% 21,935 17.6% 21,935 17.6% 1.00
Northeast 423,934 29.5% 390,134 29.7% 33,800 27.1% 67,594 27.1% 33,797 27.1% 33,797 27.1%
South 523,112 36.4% 480,680 36.7% 42,432 34.0% 84,618 33.9% 42,309 33.9% 42,309 33.9%
West 217,935 15.2% 191,260 14.6% 26,675 21.4% 53,350 21.4% 26,675 21.4% 26,675 21.4%
Insurance
Commercial 587,847 40.9% 552,487 42.1% 35,360 28.3% <0.001 70,725 28.4% 35,365 28.4% 35,360 28.4% 1.00
Dual 54,851 3.8% 46,371 3.5% 8,480 6.8% 16,696 6.7% 8,342 6.7% 8,354 6.7%
Medicaid 320,434 22.3% 296,591 22.6% 23,843 19.1% 47,674 19.1% 23,832 19.1% 23,842 19.1%
Medicare 473,168 32.9% 416,008 31.7% 57,160 45.8% 114,337 45.8% 57,177 45.8% 57,160 45.8%
PCP Visit 2019
No 508,587 35.4% 473,241 36.1% 35,346 28.3% <0.001 70,689 28.3% 35,343 28.3% 35,346 28.3% 0.99
Yes 927,713 64.6% 838,216 63.9% 89,497 71.7% 178,743 71.7% 89,373 71.7% 89,370 71.7%
Continuous Outcomes
mean SD mean SD mean SD p-value mean SD mean SD mean SD p-value
CCI 1.12 1.79 1.13 1.79 1.02 1.86 <0.001 1.02 1.85 1.02 1.84 1.02 1.86 0.49

BP: bisphosphonate; CCI: Charlson Comorbidity Index; PCP: primary care physician; SD: standard deviation.