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. 2023 Aug 3;12:e79548. doi: 10.7554/eLife.79548

Appendix 2—table 30. Antihypertensive Cohort (All Regions), Patient Characteristics Pre/Post Match.

All Observations by Antihypertensive Use: Unmatched All Observations by Antihypertensive Use: Matched
All HTN Non-users HTN Users p-value All HTN Non-users HTN Users p-value
N % N % N % N % N % N %
All Patients 7,906,603 100.0% 5,805,483 73.4% 2,101,120 26.6% 3,572,002 100.0% 1,786,001 50.0% 1,786,001 50.0%
Age
≤20 1,840,050 23.3% 1,823,229 31.4% 16,821 0.8% <0.001 33,574 0.9% 16,785 0.9% 16,789 0.9% 0.44
21-40 1,446,999 18.3% 1,299,520 22.4% 147,479 7.0% 293,445 8.2% 146,712 8.2% 146,733 8.2%
41-50 925,309 11.7% 685,931 11.8% 239,378 11.4% 463,130 13.0% 231,312 13.0% 231,818 13.0%
51-60 1,250,190 15.8% 759,987 13.1% 490,203 23.3% 870,549 24.4% 434,995 24.4% 435,554 24.4%
61-70 1,181,261 14.9% 626,235 10.8% 555,026 26.4% 918,823 25.7% 459,192 25.7% 459,631 25.7%
71-80 783,775 9.9% 381,957 6.6% 401,818 19.1% 619,578 17.3% 309,898 17.4% 309,680 17.3%
≥81 479,019 6.1% 228,624 3.9% 250,395 11.9% 372,903 10.4% 187,107 10.5% 185,796 10.4%
Gender
Female 4,670,960 59.1% 3,402,357 58.6% 1,268,603 60.4% <0.001 2,159,365 60.5% 1,079,468 60.4% 1,079,897 60.5% 0.64
Male 3,235,643 40.9% 2,403,126 41.4% 832,517 39.6% 1,412,637 39.5% 706,533 39.6% 706,104 39.5%
Region
Midwest 1,467,802 18.6% 1,065,772 18.4% 402,030 19.1% <0.001 694,206 19.4% 347,103 19.4% 347,103 19.4% 1.00
Northeast 2,152,560 27.2% 1,568,239 27.0% 584,321 27.8% 997,132 27.9% 498,566 27.9% 498,566 27.9%
South 3,042,604 38.5% 2,240,163 38.6% 802,441 38.2% 1,338,570 37.5% 669,285 37.5% 669,285 37.5%
West 1,243,637 15.7% 931,309 16.0% 312,328 14.9% 542,094 15.2% 271,047 15.2% 271,047 15.2%
Insurance
Commercial 3,938,603 49.8% 3,060,354 52.7% 878,249 41.8% <0.001 1,695,516 47.5% 848,106 47.5% 847,410 47.4% 0.80
Dual 156,497 2.0% 55,827 1.0% 100,670 4.8% 93,467 2.6% 46,774 2.6% 46,693 2.6%
Medicaid 2,594,500 32.8% 2,091,349 36.0% 503,151 23.9% 812,737 22.8% 406,012 22.7% 406,725 22.8%
Medicare 1,217,003 15.4% 597,953 10.3% 619,050 29.5% 970,282 27.2% 485,109 27.2% 485,173 27.2%
PCP Visit 2019
No 4,283,697 54.2% 3,531,914 60.8% 751,783 35.8% <0.001 1,438,005 40.3% 719,756 40.3% 718,249 40.2% 0.10
Yes 3,622,906 45.8% 2,273,569 39.2% 1,349,337 64.2% 2,133,997 59.7% 1,066,245 59.7% 1,067,752 59.8%
Continuous Outcomes
mean SD mean SD mean SD p-value mean SD mean SD mean SD p-value
CCI 0.62 1.38 0.43 1.14 1.13 1.80 <0.001 0.95 1.65 0.96 1.66 0.95 1.64 <0.05

CCI: Charlson Comorbidity Index; HTN: antihypertensive; PCP: primary care physician; SD: standard deviation.