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. 2023 Aug 3;12:e79548. doi: 10.7554/eLife.79548

Appendix 2—table 32. Antihypertensive User Cohort (All Regions) by BP Use, Patient Characteristics Pre/Post Match of BP Users/Non-users.

All Antihypertensive Users by BP: Unmatched All Antihypertensive Users by BP: Matched
All BP Non-user BP User p-value All BP Non-user BP User p-value
N % N % N % N % N % N %
All Patients 1,786,001 100.0% 1,579,388 88.4% 206,613 11.6% 408,792 100.0% 204,396 50.0% 204,396 50.0%
Age
≤20 16,789 0.9% 16,586 1.1% 203 0.1% <0.001 411 0.1% 208 0.1% 203 0.1% 1.00
21-40 146,733 8.2% 145,872 9.2% 861 0.4% 1,728 0.4% 868 0.4% 860 0.4%
41-50 231,818 13.0% 229,150 14.5% 2,668 1.3% 5,333 1.3% 2,667 1.3% 2,666 1.3%
51-60 435,554 24.4% 413,155 26.2% 22,399 10.8% 44,796 11.0% 22,399 11.0% 22,397 11.0%
61-70 459,631 25.7% 390,664 24.7% 68,967 33.4% 137,730 33.7% 68,862 33.7% 68,868 33.7%
71-80 309,680 17.3% 237,749 15.1% 71,931 34.8% 140,882 34.5% 70,439 34.5% 70,443 34.5%
≥81 185,796 10.4% 146,212 9.3% 39,584 19.2% 77,912 19.1% 38,953 19.1% 38,959 19.1%
Gender
Female 1,079,897 60.5% 894,472 56.6% 185,425 89.7% <0.001 366,424 89.6% 183,212 89.6% 183,212 89.6% 1.00
Male 706,104 39.5% 684,916 43.4% 21,188 10.3% 42,368 10.4% 21,184 10.4% 21,184 10.4%
Region
Midwest 347,103 19.4% 313,523 19.9% 33,580 16.3% <0.001 67,058 16.4% 33,529 16.4% 33,529 16.4% 1.00
Northeast 498,566 27.9% 444,828 28.2% 53,738 26.0% 107,150 26.2% 53,575 26.2% 53,575 26.2%
South 669,285 37.5% 595,410 37.7% 73,875 35.8% 146,890 35.9% 73,445 35.9% 73,445 35.9%
West 271,047 15.2% 225,627 14.3% 45,420 22.0% 87,694 21.5% 43,847 21.5% 43,847 21.5%
Insurance
Commercial 847,410 47.4% 787,519 49.9% 59,891 29.0% <0.001 119,737 29.3% 59,863 29.3% 59,874 29.3% 1.00
Dual 46,693 2.6% 37,153 2.4% 9,540 4.6% 17,884 4.4% 8,945 4.4% 8,939 4.4%
Medicaid 406,725 22.8% 369,893 23.4% 36,832 17.8% 70,769 17.3% 35,387 17.3% 35,382 17.3%
Medicare 485,173 27.2% 384,823 24.4% 100,350 48.6% 200,402 49.0% 100,201 49.0% 100,201 49.0%
PCP Visit 2019
No 718,249 40.2% 633,042 40.1% 85,207 41.2% <0.001 168,255 41.2% 84,128 41.2% 84,127 41.2% 1.00
Yes 1,067,752 59.8% 946,346 59.9% 121,406 58.8% 240,537 58.8% 120,268 58.8% 120,269 58.8%
Continuous Outcomes
mean SD mean SD mean SD p-value mean SD mean SD mean SD p-value
CCI 0.95 1.64 0.95 1.64 0.94 1.68 0.02 0.95 1.67 0.95 1.67 0.95 1.68 0.68

BP: bisphosphonate; CCI: Charlson Comorbidity Index; PCP: primary care physician; SD: standard deviation.