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. 2023 Aug 3;12:e79548. doi: 10.7554/eLife.79548

Appendix 2—table 34. Antihypertensive Non-user Cohort (All Regions) by BP Use, Patient Characteristics Pre/Post Match of BP Users/Non-users.

All Antihypertensive Non-users by BP: Unmatched All Antihypertensive Non-users by BP: Matched
All BP Non-user BP User p-value All BP Non-user BP User p-value
N % N % N % N % N % N %
All Patients 1,786,001 100.0% 1,649,985 92.4% 136,016 7.6% 271,448 100.0% 135,724 50.0% 135,724 50.0%
Age
≤20 16,785 0.9% 16,767 1.0% 18 0.0% <0.001 34 0.0% 16 0.0% 18 0.0% 1.00
21-40 146,712 8.2% 146,210 8.9% 502 0.4% 1,009 0.4% 507 0.4% 502 0.4%
41-50 231,312 13.0% 228,725 13.9% 2,587 1.9% 5,163 1.9% 2,577 1.9% 2,586 1.9%
51-60 434,995 24.4% 410,636 24.9% 24,359 17.9% 48,700 17.9% 24,349 17.9% 24,351 17.9%
61-70 459,192 25.7% 404,445 24.5% 54,747 40.3% 109,415 40.3% 54,711 40.3% 54,704 40.3%
71-80 309,898 17.4% 271,617 16.5% 38,281 28.1% 76,139 28.0% 38,070 28.0% 38,069 28.0%
≥81 187,107 10.5% 171,585 10.4% 15,522 11.4% 30,988 11.4% 15,494 11.4% 15,494 11.4%
Gender
Female 1,079,468 60.4% 956,403 58.0% 123,065 90.5% <0.001 245,537 90.5% 122,762 90.4% 122,775 90.5% 0.93
Male 706,533 39.6% 693,582 42.0% 12,951 9.5% 25,911 9.5% 12,962 9.6% 12,949 9.5%
Region
Midwest 347,103 19.4% 321,267 19.5% 25,836 19.0% <0.001 51,638 19.0% 25,819 19.0% 25,819 19.0% 1.00
Northeast 498,566 27.9% 463,273 28.1% 35,293 25.9% 70,544 26.0% 35,272 26.0% 35,272 26.0%
South 669,285 37.5% 622,064 37.7% 47,221 34.7% 93,980 34.6% 46,990 34.6% 46,990 34.6%
West 271,047 15.2% 243,381 14.8% 27,666 20.3% 55,286 20.4% 27,643 20.4% 27,643 20.4%
Insurance
Commercial 848,106 47.5% 798,579 48.4% 49,527 36.4% <0.001 99,039 36.5% 49,523 36.5% 49,516 36.5% 1.00
Dual 46,774 2.6% 40,212 2.4% 6,562 4.8% 12,645 4.7% 6,319 4.7% 6,326 4.7%
Medicaid 406,012 22.7% 381,472 23.1% 24,540 18.0% 49,025 18.1% 24,516 18.1% 24,509 18.1%
Medicare 485,109 27.2% 429,722 26.0% 55,387 40.7% 110,739 40.8% 55,366 40.8% 55,373 40.8%
PCP Visit 2019
No 719,756 40.3% 676,255 41.0% 43,501 32.0% <0.001 86,956 32.0% 43,478 32.0% 43,478 32.0% 1.00
Yes 1,066,245 59.7% 973,730 59.0% 92,515 68.0% 184,492 68.0% 92,246 68.0% 92,246 68.0%
Continuous Outcomes
mean SD mean SD mean SD p-value mean SD mean SD mean SD p-value
CCI 0.96 1.66 0.96 1.65 0.88 1.76 <0.001 0.88 1.75 0.88 1.74 0.88 1.75 0.76

BP: bisphosphonate; CCI: Charlson Comorbidity Index; PCP: primary care physician; SD: standard deviation.