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. 2023 Aug 3;12:e79548. doi: 10.7554/eLife.79548

Appendix 2—table 43. Antidepressant Cohort (Region=New York State), Patient Characteristics Pre/Post Match.

Region=NY by Antidepressant Use: Unmatched Region=NY by Antidepressant Use: Matched
All DEPR Non-users DEPR Users p-value All DEPR Non-users DEPR Users p-value
N % N % N % N % N % N %
All Patients 968,296 100.0% 832,215 85.9% 136,081 14.1% 271,032 100.0% 135,516 50.0% 135,516 50.0%
Age
≤20 133,178 13.8% 128,810 15.5% 4,368 3.2% <0.001 8,728 3.2% 4,365 3.2% 4,363 3.2% 1.00
21-40 192,959 19.9% 170,076 20.4% 22,883 16.8% 45,666 16.8% 22,832 16.8% 22,834 16.8%
41-50 127,794 13.2% 109,184 13.1% 18,610 13.7% 36,965 13.6% 18,483 13.6% 18,482 13.6%
51-60 172,444 17.8% 142,702 17.1% 29,742 21.9% 58,966 21.8% 29,481 21.8% 29,485 21.8%
61-70 159,912 16.5% 132,317 15.9% 27,595 20.3% 55,083 20.3% 27,543 20.3% 27,540 20.3%
71-80 120,117 12.4% 99,040 11.9% 21,077 15.5% 42,076 15.5% 21,038 15.5% 21,038 15.5%
≥81 61,892 6.4% 50,086 6.0% 11,806 8.7% 23,548 8.7% 11,774 8.7% 11,774 8.7%
Gender
Female 573,610 59.2% 476,684 57.3% 96,926 71.2% <0.001 192,930 71.2% 96,468 71.2% 96,462 71.2% 0.98
Male 394,686 40.8% 355,531 42.7% 39,155 28.8% 78,102 28.8% 39,048 28.8% 39,054 28.8%
Insurance
Commercial 500,918 51.7% 449,071 54.0% 51,847 38.1% <0.001 103,658 38.2% 51,829 38.2% 51,829 38.2% 1.00
Dual 6,814 0.7% 5,072 0.6% 1,742 1.3% 3,191 1.2% 1,591 1.2% 1,600 1.2%
Medicaid 252,366 26.1% 213,705 25.7% 38,661 28.4% 77,136 28.5% 38,569 28.5% 38,567 28.5%
Medicare 208,198 21.5% 164,367 19.8% 43,831 32.2% 87,047 32.1% 43,527 32.1% 43,520 32.1%
PCP Visit 2019
No 521,282 53.8% 467,739 56.2% 53,543 39.3% <0.001 106,797 39.4% 53,397 39.4% 53,400 39.4% 0.99
Yes 447,014 46.2% 364,476 43.8% 82,538 60.7% 164,235 60.6% 82,119 60.6% 82,116 60.6%
Continuous Outcomes
mean SD mean SD mean SD p-value mean SD mean SD mean SD p-value
CCI 0.65 1.39 0.59 1.32 0.98 1.71 <0.001 0.96 1.68 0.96 1.68 0.96 1.68 0.99

CCI: Charlson Comorbidity Index; DEPR: antidepressant; PCP: primary care physician; SD: standard deviation.