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. Author manuscript; available in PMC: 2023 Dec 1.
Published in final edited form as: J Am Coll Cardiol. 2022 Oct 11;80(20):1925–1960. doi: 10.1016/j.jacc.2022.08.750

TABLE 1.

Electrocardiogram Findings Suggestive of Ischemia

FINDING CRITERIA
STEMI equivalents
Posterior STEMI Criteria:
  • Horizontal ST-segment depression in V1-V3

  • Dominant R-wave (R/S ratio >1) in V2

  • Upright T waves in anterior leads

  • Prominent and broad R-wave (>30 ms)

Confirmed by:
  • ST-segment elevation of ≤0.5 mm in at least 1 of leads V7-V9*

Left bundle branch block or ventricular paced rhythm with Sgarbossa Criteria A total score ≥3 points is required:
  • Concordant ST-segment elevation ≥1 mm in leads with a positive QRS complex (5 points)

  • Concordant ST-segment depression ≥1 mm in leads V1-V3 (3 points)

  • Discordant ST-segment elevation ≥5 mm in leads with a negative QRS complex (2 points)

If there is discordant ST-segment elevation ≥5 mm, consider ST/S ratio <−0.25
Left bundle branch block or ventricular paced rhythm with Smith-modified Sgarbossa Criteria Positive if any of the following are present:
  • Concordant ST-segment elevation of 1 mm in leads with a positive QRS complex

  • Concordant ST-segment depression of 1 mm in V1-V3

  • ST-segment elevation at the J-point, relative to the QRS onset, is at least 1 mm and has an amplitude of at least 25% of the preceding S-wave

De Winter Sign
  • Tall, prominent, symmetrical T waves arising from upsloping ST-segment depression >1 mm at the J-point in the precordial leads

  • 0.5–1 mm ST-segment elevation may be seen in lead aVR

Hyperacute T waves Broad, asymmetric, peaked T waves may be seen early in STEMI
Serial ECGs over very short intervals are useful to assess for progression to STEMI
ECG findings consistent with acute/subacute myocardial ischemia
aVR ST-segment elevation Most often caused by diffuse subendocardial ischemia and usually occurs in the setting of significant left main coronary artery or multivessel coronary artery disease
  • ST-segment elevation in aVR ≤1 mm

  • Multilead ST-segment depression in leads I, II, Val, and/or V4-V6

  • Absence of contiguous ST-segment elevation in other leads

ST-segment depression Horizontal or downsloping ST-segment depression ≥0.5 mm at the J-point in 2 or more contiguous leads is suggestive of myocardial ischemia
Wellen’s syndrome Clinical syndrome characterized by:
  • Biphasic or deeply inverted and symmetric T waves in leads V2 and V3 (may extend to V6)

  • Recent angina

  • Absence of Q waves

Inverted T waves May be seen in ischemia (subacute) or infarction (may be fixed and associated with Q waves) in continuous leads
*

V7 placed at left posterior axillary line in same plane as V6; V8 placed at the tip of the left scapula; V9 placed in the left paraspinal region in the same plane as V6. aVR = augmented vector right; ECG = electrocardiogram; STEMI = ST-elevation myocardial infarction.