Table 3.
Performance of COPD diagnostic questionnaires in study population.
| Questionnaire cutoff points | Se (CI 95%) | Sp (CI 95%) | VPP (CI 95%) | VPN (CI 95%) | LR+ (CI 95%) | LR−· (CI 95%) | AUC (CI 95%) | pvalue |
|---|---|---|---|---|---|---|---|---|
| LFQ ≤18 | 60.1 (56.4–63.8) | 19.3 (16.3–22.2) | 66.3 (62.7–69.8) | 15.5 (12.7–18.2) | 1.34 (0.98–1.83) | 0.48 (0.35–0.66) | 0.66 (0.67–0.71) | <0.001 |
| CDQ ≥16 | 78.6 (75.5–81.7) | 47.4 (43.6–51.1) | 42.8 (39.0–46.5) | 81.6 (78.7–84.S) | 1.49 (1.33–1.67) | 0.45 (0.40–0.50) | 0.68 (0.61−0.73) | <0.001 |
| PUMA ≥S | 58.8 (55.1–62.5) | 64.2 (60.67.8) | 38.3 (34.7–42.0) | 80.5 (77.5–83.4) | 1.64 (1.38–1.94) | 0.64 (0.54–0.75) | 0.67 (0.62–0.71) | <0.001 |
| COULD IT BE COPD ≥3 | 58.8 (55.1–62.5) | 53.2 (49.5–57) | 32.3 (28.7–35.8) | 77.4 (74.2–80.5) | 1.26 (1.08–1.46) | 0.77 (0.66–0.90) | 0.58 (0.61–0.63) | 0.001 |
| COPD-PS ≥4 | 78.6 (75.5–87.5) | 44.3 (33.5–55.2) | 34.8 (24.5–45.2) | 84.6 (76.7–92.4) | 1.41 (1.26–1.57) | 0.48 (0.43–0.53) | 0.65 (0.66–0.69) | <0.001 |
Se, sensitivity; Sp, specificity; PPV, positive predictive value; NPV, negative predictive value; LR+, positive likelihood ratio; LR−, negative likelihood ratio; AUC, area under the receiver operating characteristic curve.