Table 1.
Baseline characteristics
| Overall (n = 216) | NA (n = 117) | Non-NA (n = 99) | p-value | ||
|---|---|---|---|---|---|
| General information | |||||
| Age, year | 64.00 (56.00–71.00) | 65.00 (56.50–71.00) | 63.00 (55.00–70.00) | 0.356 | |
| Male | 172 (79.6) | 93 (79.5) | 79 (79.8) | 0.955 | |
| Current smoker | 74 (34.3) | 42 (35.9) | 32 (32.3) | 0.581 | |
| Hypertension | 128 (59.3) | 67 (57.3) | 61 (61.6) | 0.517 | |
| Diabetes mellitus | 68 (31.5) | 34 (29.1) | 34 (34.3) | 0.405 | |
| LVEF, % | 56.00 (49.25-61.00) | 56.00 (46.00–59.00) | 57.00 (50.00–61.00) | 0.077 | |
| Creatinine, µmol/L | 84.00 (70.00-100.00) | 85.00 (70.50–101.00) | 83.00 (69.00–99.00) | 0.179 | |
| eGFR, mL/min/1.73 m2 | 107.74 ± 33.85 | 103.48 ± 32.96 | 112.76 ± 34.37 | 0.044 | |
| eGFR < 60, mL/min/1.73 m2 | 15 (6.9) | 12 (10.3) | 3 (3.0) | 0.037 | |
| Fasting blood glucose, mmol/L | 5.75 (4.91–6.77) | 5.78 (4.89–6.75) | 5.70 (4.98–6.77) | 0.566 | |
| TG, mmol/L | 1.69 (1.24–2.56) | 1.92 (1.30–2.79) | 1.55 (1.19–2.37) | 0.039 | |
| TC, mmol/L | 3.88 (3.42–4.83) | 4.13 (3.3.55–5.28) | 3.79 (3.21–4.41) | 0.004 | |
| HDL-C, mmol/L | 1.11 (0.94–1.25) | 1.05 (0.93–1.24) | 1.15 (0.95–1.29) | 0.054 | |
| LDL-C, mmol/L | 2.38 (1.98–2.89) | 2.56 (2.08–3.13) | 2.17 (1.72–2.71) | < 0.001 | |
| APOA1, g/L | 1.20 (1.07–1.33) | 1.18 (1.06–1.32) | 1.22 (1.11–1.34) | 0.401 | |
| APOB, g/L | 0.73 (0.60–0.90) | 0.78 (0.62–0.97) | 0.67 (0.57–0.84) | 0.003 | |
| APOB/A1 | 0.61 (0.49–0.77) | 0.65 (0.53–0.89) | 0.55 (0.47–0.69) | 0.003 | |
| Stent age, months | 48.00 (25.25-84.00) | 60 (31.00–96.00) | 48.00 (24.00–72.00) | 0.023 | |
| Clinical presentation | |||||
| ACS at stenting | 85 (39.4) | 50 (42.7) | 35 (35.4) | 0.269 | |
| ACS at restenosis | 63 (29.2) | 48 (41.0) | 15 (15.2) | < 0.001 | |
| Medication at restenosis | |||||
| Aspirin | 176 (81.5) | 92 (78.6) | 84 (84.8) | 0.241 | |
| Statin | 183 (84.7) | 97 (82.9) | 86 (86.9) | 0.420 | |
| ACEI/ARB | 176 (81.5) | 90 (76.9) | 86 (86.9) | 0.061 | |
| β-blocker | 179 (82.9) | 96 (82.1) | 83 (83.8) | 0.728 | |
| Insulin | 12 (5.6) | 5 (4.3) | 7 (7.1) | 0.371 | |
Data are expressed as the median (interquartile range), mean ± SD, or n (%). ACEI: angiotensin-converting enzyme inhibitor; ACS: acute coronary syndrome; APO: apolipoprotein; ARB: angiotensin receptor blocker; eGFR, estimated glomerular filtration rate; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; LVEF: left ventricular ejection fraction; NA: neoatherosclerosis; TC: total cholesterol; TG: triglyceride