Table 3.
Optical coherence tomography characteristics
| Overall (n = 216) | NA (n = 117) | Non-NA (n = 99) | p-value | |||
|---|---|---|---|---|---|---|
| Quantitative analysis | ||||||
| MLA, mm2 | 1.68 ± 0.58 | 1.61 ± 0.63 | 1.76 ± 0.52 | 0.067 | ||
| Stent area (MLA site), mm2 | 6.58 ± 1.62 | 6.50 ± 1.58 | 6.68 ± 1.67 | 0.435 | ||
| Neointimal tissue area (MLA site), mm 2 | 4.90 ± 1.47 | 4.89 ± 1.45 | 4.92 ± 1.49 | 0.881 | ||
| Burden of neointimal tissue (MLA site), % | 73.81 ± 8.73 | 74.61 ± 9.48 | 72.86 ± 7.70 | 0.136 | ||
| Qualitative analysis | ||||||
|
Neointima characteristics at entire stent |
||||||
| NA with lipid | 112 (51.9) | 112 (95.7) | 0 (0.0) | < 0.001 | ||
| NA with calcium | 40 (18.5) | 40 (34.2) | 0 (0.0) | < 0.001 | ||
| TCFA | 42 (19.4) | 42 (35.9) | 0 (0.0) | < 0.001 | ||
| Intimal disruption | 40 (18.5) | 40 (34.2) | 0 (0.0) | < 0.001 | ||
| Plaque erosion | 60 (27.8) | 52 (44.4) | 8 (8.1) | < 0.001 | ||
| NV | 96 (44.4) | 62 (53.0) | 34 (34.3) | 0.006 | ||
| Thrombus | 54 (25.0) | 46 (39.3) | 8 (8.1) | < 0.001 | ||
|
Neointima characteristics at MLA site |
||||||
| Homogeneous | 44 (20.4) | 8 (6.8) | 36 (36.4) | < 0.001 | ||
| Heterogeneous | 172 (79.6) | 109 (93.2) | 63 (63.6) | < 0.001 | ||
| TCFA | 28 (13.0) | 28 (23.9) | 0 (0.0) | < 0.001 | ||
| Intimal disruption | 25 (11.6) | 25 (21.4) | 0 (0.0) | < 0.001 | ||
| Thrombus | 27 (12.5) | 27 (23.1) | 0 (0.0) | < 0.001 | ||
Data are expressed as the median (interquartile range) or n (%). MLA: minimum lumen area; NA: neoatherosclerosis; NV: neovascularization; TCFA: thin-cap fibroatheroma