Skip to main content
. 2023 May 12;192(6):3109–3115. doi: 10.1007/s11845-023-03393-8

Table 2.

Comparison of parameters with the severity of pruritus

Characteristics No Pruritus
(n = 53; 44%)
Pruritus
(n = 67; 56%)
p-value
Mild
(n = 49; 73%)
Moderate
(n = 13; 19.4%)
Severe
(n = 5; 7.6%)
Age (in years) 52.3 ± 14.5 54.3 ± 11.3 58.3 ± 15.6 57 ± 6.9 0.46
Gender
   Males 39(73.5%) 40(81.6%) 10 (76.9%) 5(100%) 0.49
   Females 14 (26.5%) 9(18.4%) 3(23.1%) None
Etiology of ESKD
   DKD 6(11.3%) 11 (22.4%) 3 (23%) 2 (40%) 0.25
   CGN 11 (20.7%) 17 (34.6%) 6 (46.2%) 1 (20%) 0.2
   CTIN 18 (34%) 6 (12.3%) 2 (15.4%) 1 (20%) 0.06
   HNS 9 (17.1%) 7 (14.3%) 2 (15.4%) None 0.78
   ADPKD 3 (5.6%) None None 1 (20%) 0.06
   Others 6 (11.3%) 8 (16.4%) None None 0.33
Seropositive
   HBV None 1 (2%) None 2 (40%)
   HCV None 1 (2%) None None
Smoking Status
   Smokers 2 (3.8%) 3 (6.1%) None None 0.73
   Non Smokers 51 (96.2%) 46 (93.9%) 13(100%) 5(100%)
Dialysis Vintage
   < 5 years 30 (56.6%) 28 (57.1%) 6 (46.1%) 2 (40%) 0.79
   > 5 years 23 (43.4%) 21 (42.9%) 7 (53.9%) 3 (60%)
Dialysis Adequacy
   Kt/v 1.53 ± 0.38 1.41 ± 0.28 1.35 ± 0.22 1.47 ± 0.28 0.17
Dialysis Frequency (per week)
   twice 47 (88.6%) 48 (97.9%) 12 (92.3%) 5 (100%) 0.27
   thrice 6 (11.4%) 1 (2.1%) 1 (7.7%) None
Laboratory parameters
   Hemoglobin (g/dl) 10.06 ± 1.51 9.65 ± 1.31 9.8 ± 1.9 9.12 ± 1.17 0.37
   Albumin (g/dl) 4.03 ± 0.41 4 ± 0.35 4.32 ± 0.44 3.98 ± 0.34 0.06
   Calcium (mg/dL) 8.66 ± 0.72 8.53 ± 0.78 8.07 ± 0.9 8.56 ± 0.62 0.11
   Phosphorus (mg/dL) 5.09 ± 1.91 5.23 ± 1.85 1.62 ± 0.45 4.78 ± 1.33 0.58
   PTH (pg/mL) 216(106,529) 340(154,529) 212(145,452) 150(290,505) 0.45
SKINDEX-10
Symptoms None 5 (2,7) 8 (6,10) 13 (12,16)  < 0.001
   Emotions None 4 (3,7) 9 (7,11) 11 (9,15)  < 0.001
   Functioning None 4 (2,8) 10 (4,12) 10 (6.5,21.5) 0.01
itch-MOS score
   Total Score None 44.91 ± 8.03 41.23 ± 7.91 40.91 ± 7.32 0.67
   Sleep hours/day 6.65 ± 1.31 6.67 ± 1.74 5.76 ± 1.69 3 ± 1.41  < 0.001

DKD Diabetic kidney disease, CGN chronic glomerulonephritis, CTIN chronic tubulointerstitial nephritis, HNS hypertensive nephrosclerosis, ADPKD autosomal dominant polycystic kidney disease, HBV hepatitis B virus, HCV hepatitis C virus