Table 1.

List of abbreviations

Abbreviation	Meaning
POP	Pelvic organ prolapse
PFD	Pelvic floor disorder
USL	Uterosacral ligament
IHC	Immunohistochemical staining
POP-Q	Pelvic organ prolapse quantification system
Fibrillar Collagen	Trichrome stainable fibrillar collagen
Total Non-Vascular Smooth Muscle	Non-vascular, fascicular smooth muscle
SmFDO	Smooth muscle fiber dropout
Muscle Fiber Vesicles	Small vesicles found in some of the non-vascular smooth muscle cells
Adipose	Adipose found in the uterosacral ligament
PMN-Inflam	Neutrophil inflammation of the uterosacral ligament
PN-Inflam	Neutrophil inflammation surrounding the uterosacral ligament neural bundles
NIH	Neo-intimal hyperplasia
Vessel Quantity	Relative uterosacral ligament vascular quantity
POP-HQ	Pelvic organ prolapse histologic quantification system
POP-A	Prolapse adipose phenotype
POP-I	Prolapse inflammation phenotype
POP-V	Prolapse-vascular phenotype
ER	Estrogen receptor
ERa	Estrogen receptor alpha
ERb	Estrogen receptor beta
GPER	G-protein estrogen receptor
AR	Androgen receptor
ERa-SM	Estrogen receptor alpha in non-vascular, fascicular smooth muscle
ERa-CT	Estrogen receptor alpha in connective tissue
ERb-SM	Estrogen receptor beta in non-vascular, fascicular smooth muscle
ERb-ASM	Estrogen receptor beta in arterial tunica media smooth muscle
ERb-EC	Estrogen receptor beta in endothelial cells
ERb-CT	Estrogen receptor beta in connective tissue
GPER-SM	G-protein couple estrogen receptor in non-vascular, fascicular smooth muscle
GPER-ASM	G-protein couple estrogen receptor in arterial tunica media smooth muscle
GPER-EC	G-protein couple estrogen receptor in endothelial cells
GPER-CT	G-protein couple estrogen receptor in connective tissue
AR-SM	Androgen receptor in non-vascular, fascicular smooth muscle
AR-CT	Androgen receptor in connective tissue