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. 2023 Feb 20;192(6):2917–2927. doi: 10.1007/s11845-023-03300-1

Table 4.

Absolute and relative frequencies of FORTA category C drugs (i.e. drugs with questionable efficacy–safety profiles in elderly people) and FORTA category D drugs (i.e. drugs that should be avoided in elderly people) with a suspected relationship to adverse drug reactions in the study population

FORTA category C and D drugs with a suspected relationship to ADR occurrence n %a
FORTA category C drugs 67 100
  Risperidone 11 16.4
  Pipamperone 8 11.9
 Olanzapine 7 10.4
  Quetiapine 6 9.0
  Venlafaxine 6 9.0
  Mirtazapine 5 7.5
  Spironolactone 4 6.0
  Amitriptyline 3 4.5
  Duloxetine 3 4.5
  Digoxin 2 3.0
  Melperone 2 3.0
  Tramadol 2 3.0
  Valproic acid 2 3.0
  Digitoxin 1 1.5
  Doxepin 1 1.5
  Gabapentin 1 1.5
  Oxycodone 1 1.5
  Tilidine 1 1.5
  Zopiclone 1 1.5
FORTA category D drugs 21 100
  Aripiprazole 6 28.6
  Haloperidol 4 19.0
  Carbamazepine 3 14.3
  Clozapine 3 14.3
  Opipramol 3 14.3
  Ciprofloxacin 1 4.8
  Prednisolone 1 4.8

ADR denotes adverse drug reaction, FORTA Fit fOR The Aged

aPercentages may not total 100 due to rounding