Table 2.
Effect of C. equisetifolia extract incorporated with gold nanoparticles (Au-NPs) against toxicity induced by chlorpyrifos (CPF) on the biochemical measurements related to the integrity of liver and brain tissues of rats
| C | Au-C. equisetifolia nano-extract | CPF | CPF + Au-C. equisetifolia nano-extract | ||
|---|---|---|---|---|---|
| Pre-treated | Post-treated | ||||
| Liver | |||||
| TNF-α (pg/g tissue) | 344.00 ± 0.95 | 343.20 ± 0.58 | 726.40 ± 1.50a | 427.40 ± 1.03ab | 591.60 ± 1.17ab |
| IL-6 (pg/g tissue) | 415.40 ± 1.29 | 415.60 ± 1.50 | 877.17 ± 1.67a | 516.11 ± 1.66ab | 714.40 ± 2.12ab |
| Hydroxyproline (kg/mg tissue) | 0.32 ± 0.00 | 0.33 ± 0.01 | 0.68 ± 0.01a | 0.40 ± 0.01ab | 0.55 ± 0.01ab |
| AChE (ng/g tissue) | 0.50 ± 0.02 | 0.48 ± 0.02 | 0.31 ± 0.02a | 0.30 ± 0.02a | 0.29 ± 0.02a |
| Brain | |||||
| TNF-α (pg/g tissue) | 133.00 ± 0.55 | 134.00 ± 0.63 | 280.86 ± 1.65a | 165.26 ± 1.27ab | 228.73 ± 1.06ab |
| IL-6 (pg/g tissue) | 224.80 ± 1.32 | 225.60 ± 0.60 | 474.68 ± 2.21a | 279.30 ± 1.73ab | 386.61 ± 2.37ab |
| β-Amyloid (pg/g tissue) | 6.19 ± 0.01 | 6.19 ± 0.01 | 13.08 ± 0.04a | 7.69 ± 0.03ab | 10.65 ± 0.01ab |
| AChE (ng/g tissue) | 9.37 ± 0.45 | 10.93 ± 0.79 | 7.63 ± 0.46a | 10.76 ± 0.44b | 9.60 ± 0.35b |
Data were calculated from five replicates and expressed as mean ± SE
aSignificant versus control group at P ≤ 0.05
bSignificant versus toxic (CPF) group at P ≤ 0.05