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. 2023 Aug 14;44(12):2469–2478. doi: 10.1038/s41401-023-01143-1

Fig. 1. Fraxinellone dose-dependently alleviated DSS-induced pathological impairment in mice.

Fig. 1

a Chemical structure of fraxinellone and schematic overview of the intestinal fibrosis model. b Body weights and (c) DAI of each group during the experimental process. d Colorectal tissue lesions were photographed and recorded. e Changes in colon length. f–g Hematoxylin and eosin (H&E) staining and histological score of colorectal tissue sections. Scale bar, 50 µm. Data are presented as the mean ± SEM (n = 3–5 per group). #P < 0.05, ##P < 0.01 vs. control group, *P < 0.05, **P < 0.01 vs. DSS model group.