Table 2.
Ongoing clinical trials on Long COVID (ClinicalTrials.gov website)*
| NCT number | Title | Interventions | |
|---|---|---|---|
| 1 | NCT05618587 | Effect of Lithium Therapy on Long COVID Symptoms |
Drug: Lithium Drug: Placebo |
| 2 | NCT04997395 | Feasibility of Cannabidiol for the Treatment of Long COVID | Drug: MediCabilis Cannabis sativa 50 |
| 3 | NCT05595369 | SARS CoV-2 Viral Persistence Study (PASC)—Study of Long COVID-19 |
Drug: Paxlovid Drug: Placebo |
| 4 | NCT05576662 | Paxlovid for Treatment of Long Covid | Drug: Nirmatrelvir + Ritonavir Drug: Placebo + Ritonavir |
| 5 | NCT05220280 | SOLIDARITY Finland Plus Long-COVID |
Drug: Imatinib Drug: Infliximab |
| 6 | NCT05513560 | Canadian Adaptive Platform Trial for Long COVID-19 |
Drug: Ibudilast Drug: Pentoxifylline Other: Placebo |
| 7 | NCT04978259 | SOLIDARITY Finland Long-COVID (Remdesivir Long-term Follow-up Study of COVID Patients) | Drug: Remdesivir |
| 8 | NCT05592418 | Study to Evaluate the Efficacy and Safety of Ampligen in Patients With Post-COVID Conditions |
Drug: Rintatolimod Other: Placebo/Normal Saline |
| 9 | NCT04604704 | Pilot Study Into LDN and NAD + for Treatment of Patients With Post-COVID-19 Syndrome |
Drug: Naltrexone Dietary Supplement: NAD + |
| 10 | NCT05216614 | Fluvoxamine to Augment Olfactory Recovery For Long COVID-19 Parosmia |
Drug: Fluvoxamine Drug: Placebo |
| 11 | NCT04695704 | Efficacy of Montelukast in Mild-moderate Respiratory Symptoms in Patients With Long-COVID-19: |
Drug: Montelukast Other: placebo |
| 12 | NCT04948203 | Assessing the Efficacy of Sirolimus in Patients With COVID-19 Pneumonia for Prevention of Post-COVID Fibrosis | Drug: Sirolimus |
| 13 | NCT05507372 | Treatment for post acute COVID-19 Syndrome | Drug: Pimozide |
| 14 | NCT04904536 | Statin TReatment for COVID-19 to Optimise NeuroloGical recovERy |
Drug: Atorvastatin Other: Standard Care |
| 15 | NCT05497089 | Temelimab as a Disease Modifying Therapy in Patients With Neuropsychiatric Symptoms in Post-COVID 19 or PASC Syndrome |
Drug: Temelimab Drug: Placebo |
| 16 | NCT05350774 | Immunotherapy for Neurological Post-Acute Sequelae of SARS-CoV-2 |
Drug: IV immunoglobulin Drug: IV normal saline Drug: IV methylprednisolone |
| 17 | NCT05430152 | Low-dose Naltrexone for Post-COVID Fatigue Syndrome | Drug: Low-Dose Naltrexone Other: Placebo |
| 18 | NCT05096884 | Post-Acute Sequelae of Coronavirus-19 (COVID-19) With Dyspnea on Exertion And Associated TaChycardia TrEatment Study | Drug: Metoprolol Succinate |
| 19 | NCT05047952 | Vortioxetine for post-COVID-19 Condition |
Drug: Vortioxetine Drug: Placebo |
| 20 | NCT05228899 | Zofin to Treat COVID-19 Long Haulers |
Drug: Zofin Other: Placebo |
| 21 | NCT05052307 | A Real-world Evidence Study of BNT162b2 mRNA Covid-19 Vaccine in Brazil | Drug: Pfizer/BioNTech BNT162b2 mRNA COVID-19 vaccine, CoronaVac COVID-19 vaccine, ChAdOx1 nCoV-19 vid-19 Vaccine, Janssen COVID-19 Vaccine |
*In the ClinicalTrials.gov database, on 29.11.2022, 333 hits were recived for the search term “long covid”. Among the ongoing clinical trials, drug intervention was performed in 21 cases. For scope reasons, studies using drugs and dietary supplements in the experimental stage have not been included in the table