Table 1:
Summary statistics for MC patients and matched reference individuals.
| Reference | MC | CC | LC | |
|---|---|---|---|---|
| n [%] | n [%] | n [%] | n [%] | |
| Total | 57,806 [100.00] | 12,140 [100.00] | 3,905 [100.00] | 8,235 [100.00] |
| Male | 16,082 [27.8] | 3,400 [28.0] | 886 [22.7] | 2,514 [30.5] |
| Female | 41,724 [72.2] | 8,740[72.0] | 3,019 [77.3] | 5,721 [69.5] |
| AGE AT START FOLLOW UP | ||||
| Mean [SD] years | 60.2 [16.8] | 60.8 [16.9] | 64.3 [14.8] | 59.2 [17.5] |
| Median [IQR] years | 63.0 [50.0–72.6] | 63.6 [50.7–73.2] | 65.9[55.9–74.9] | 62.2 [48.1–72.3] |
| < 50 years | 14,423 [25.0] | 2,925 [24.1] | 642 [16.4] | 2,283 [27.7] |
| > = 50 years | 43,383 [75.0] | 9,215 [75.9] | 3,263[83.6] | 5,952 [72.3] |
| YEARS OF FOLLOW UP | ||||
| Mean [SD] years | 9.9 [4.3] | 9.7 [4.3] | 9.6 [4.3] | 9.8 [4.3] |
| Median [IQR] years | 9.7 [6.9–13.1] | 9.6 [6.7–12.9] | 9.5 [6.8–12.8] | 9.6 [6.7–12.9] |
| < 1 years | 1,301 [2.3] | 259 [2.1] | 107 [2.7] | 152 [1.9] |
| 1 < 5 years | 5,083 [8.8] | 1,198 [9.9] | 443 [11.3] | 755 [9.2] |
| 5 < 10 years | 24,001 [41.5] | 5,138 [42.3] | 1,597 [40.9] | 3,541 [43.0] |
| > = 10 years | 27,420 [47.4] | 5,545 [45.7] | 1,758 [45.0] | 3,787 [46.0] |
| YEAR OF START FOLLOW UP | ||||
| 2003 – 2010 | 30,115 [52.1] | 6,305 [51.9] | 2,112 [54.1] | 4,193 [50.9] |
| 2011 – 2017 | 27,691 [47.9] | 5,835 [48.1] | 1,793 [45.9] | 4,042 [49.1] |
| REASON FOR END OF FOLLOW-UP | ||||
| Emigration | 731 [1.3] | 80[0.7] | 14 [0.36] | 66 [0.8] |
| 31 Dec. 2021 | 43,667 [75.5] | 8,778 [72.3] | 2,641[67.6] | 6,137 [74.5] |
| Diagnosed with MC | 99 [0.2] | 0 | 0 | 0 |
| Diagnosed with acute pancreatitis | 437 [0.8] | 146 [1.2] | 54 [1.4] | 92 [1.1] |
| Death | 12,872 [22.3] | 3,136 [25.8] | 1,196 [30.6] | 1,940 [23.6] |
| COUNTRY OF BIRTH | ||||
| Nordic | 51,118 [88.4] | 11,392 [93.8] | 3,743 [95.8] | 7,649[92.9] |
| Other | 6,688 [11.6] | 748[6.2] | 162 [4.2] | 586 [7.1] |
| EDUCATION | ||||
| Compulsory school (< = 9 yrs) | 14,382 [24.9] | 3,072 [25.3] | 1,151 [29.5] | 1,921 [23.3] |
| Upper secondary school (10–12 yrs) | 23,778 [41.1] | 4,968 [40.9] | 1,633 [41.8] | 3,335 [40.5] |
| College or university (> = 13 yrs) | 18,143 [31.4] | 3,773 [31.1] | 1,030 [26.4] | 2,743 [33.3] |
| NA | 1,503 [2.6] | 327 [2.7] | 91 [2.3] | 236 [2.9] |
| COMORBIDITY AT DIAGNOSIS DATE | ||||
| IBD | 55 [s0.1] | 336 [2.8] | 112 [2.9] | 224 [2.7] |
| Celiac disease | 39 [0.07] | 415 [3.4] | 136[3.5] | 279 [3.4] |
| MEDICATION DURING FOLLOW-UP* | ||||
| Budesonide | 132 [0.27] | 5,169 [50.1] | 1,896 [57.7] | 3,273 [46.5] |
| Thiopurines | 5 [0.01] | 224 [2.2] | 78 [2.4] | 146 [2.1] |
*
Restricted cohort including study participants enrolled after or on 2006–01–01