Table 6.
Exploratory results on the association of patient characteristics with malignancy
Characteristics | Crude OR (95% CI) | P |
---|---|---|
Age (in years) | 1.00 (0.96-1.05) | 0.967 |
Sex | ||
Female | Ref | Ref |
Male | 0.51 (0.12-2.11) | 0.351 |
Past medical history | ||
Thyroid disease | ||
Without | Ref | Ref |
With | 1.72 (0.07-44.10) | 0.743 |
Family history: Thyroid dysfunction | ||
No | Ref | Ref |
Yes | 0.51 (0.12-2.11) | 0.351 |
Family history: Thyroid malignancy | ||
No | Ref | Ref |
Yes | 1.78 (0.26-12.24) | 0.557 |
Smoking status | ||
No | Ref | Ref |
Yes | 0.53 (0.09-3.35) | 0.504 |
Alcohol consumption | ||
No | Ref | Ref |
Yes | 1.26 (0.31-5.07) | 0.746 |
Presence of obstructive symptoms | ||
No | Ref | Ref |
Yes | 0.77 (0.14-4.27) | 0.764 |
Thyroid medications | ||
No | Ref | Ref |
Yes | 0.78 (0.20-2.96) | 0.712 |
Sonographic pattern | ||
Very low/low | Ref | Ref |
Intermediate | 0.96 (0.28-3.33) | 0.949 |
High | 1.83 (0.49-6.76) | 0.368 |
Size of thyroid nodule | ||
≥1 cm | Ref | Ref |
<1 cm | 2.24 (0.34-14.81) | 0.401 |
Vascularity | ||
Non-vascular | Ref | Ref |
Vascular | 1.02 (0.20-5.26) | 0.984 |
Calcification | ||
Negative | Ref | Ref |
Positive | 1.63 (0.47-5.64) | 0.443 |
Echogenicity | ||
Isoechoic | Ref | Ref |
Hypoechoic | 1.17 (0.40-3.41) | 0.771 |
Hyperechoic | 0.60 (0.06-6.54) | 0.675 |
First FNAB | ||
Cytologic atypia | Ref | Ref |
Architectural atypia | 0.11 (0.01-1.10) | 0.061 |
Both cytologic and architectural atypia | 0.90 (0.23-3.52) | 0.876 |
Second FNAB | ||
Cytologic atypia | Ref | Ref |
Architectural atypia | 0.27 (0.04-1.68) | 0.161 |
Both cytologic and architectural atypia | 1.63 (0.44-6.07) | 0.470 |