Table 2.
Cohort 1 (Performance and Strength Cohort) Area Under the Receiver Operating Characteristic Curve and the Youden Index for Walking Speed <0.8 m/s by Age, Body Anthropometry, Body Composition Measures, and Grip Strength in Men and Women
| Variable | Women | Men | ||||||
|---|---|---|---|---|---|---|---|---|
| Area Under the Curve (95% CI), p Value |
Youden Index | Optimal Cut Point | SDOC Cut Point | Area Under the Curve (95% CI), p Value |
Youden Index | Optimal Cut Point | SDOC Cut Point | |
| Age, y | 0.67 (0.62, 0.72), <.001 |
0.28 | 76.50 | — | 0.60 (0.54, 0.66), .001 |
0.22 | 70.95 | — |
| Weight, kg | 0.55 (0.49, 0.61), .139 |
0.11 | 72.7 | — | 0.58 (0.52, 0.64), .009 |
0.17 | 68.05 | — |
| Height, m | 0.63 (0.57, 0.69), <.001 |
0.22 | 1.56 | — | 0.64 (0.57, 0.70), <.001 |
0.27 | 1.68 | — |
| BMI, kg/m2 | 0.52 (0.46, 0.58), .552 |
0.11 | 24.08 | — | 0.52 (0.46, 0.59), 0.464 |
0.12 | 24.35 | — |
| ALM | ||||||||
| ALM, kg | 0.57 (0.50, 0.63), .038 |
0.12 | 15.83 | — | 0.58 (0.51, 0.65), .009 |
0.20 | 22.62 | — |
| ALM/weight, kg/kg | 0.51 (0.45, 0.58), .663 |
0.11 | 0.22 | — | 0.52 (0.46, 0.59), 0.422 |
0.10 | 0.28 | — |
| ALM/height, kg/m | 0.54 (0.48, 0.60), .232 |
0.09 | 10.22 | — | 0.55 (0.49, 0.62), .073 |
0.16 | 12.29 | — |
| ALM/BMI kg/kg/m2 | 0.59 (0.53, 0.65), .004 |
0.21 | 0.56 | — | 0.59 (0.52, 0.65), .005 |
0.23 | 0.80 | — |
| ALM/height2 kg/m2 | 0.51 (0.45, 0.57), .841 |
0.08 | 7.24 | — | 0.51 (0.45, 0.58), 0.647 |
0.13 | 6.67 | — |
| Grip strength (GR) | ||||||||
| GR, kg | 0.68 (0.63, 0.74),<.001 |
0.28 | 20.50 | <20.00* | 0.64 (0.58, 0.70), <.001 |
0.27 | 31.05 | <35.50 kg* |
| GR/weight, kg/kg | 0.64 (0.58, 0.69), <.001 |
0.25 | 0.30 | <0.34* | 0.58 (0.51, 0.64), .01 |
0.19 | 0.38 | <0.45* |
| GR/height, kg/m | 0.67 (0.61, 0.73), <.001 |
0.29 | 13.59 | 13.13 | 0.63 (0.57, 0.70), <.001 |
0.25 | 18.41 | <22.00 |
| GR/height2 kg/kg/m2 | 0.65 (0.59, 0.71), <.001 |
0.27 | 8.40 | <8.25 | 0.62 (0.56, 0.68), <.001 |
0.19 | 9.67 | <12.13 |
| GR/BMI, kg/kg/m2 | 0.67 (0.61, 0.72), <.001 |
0.30 | 0.71 | <0.79* | 0.61 (0.54, 0.67), <.001 |
0.28 | 1.09 | <1.05* |
| GR/ALM, kg/kg | 0.64 (0.58, 0.70), <.001 |
0.25 | 1.15 | 1.36 | 0.59 (0.53, 0.66), .002 |
0.26 | 1.48 | 1.60 |
Notes: ALM = appendicular lean mass; BMI = body mass index; CI = confidence interval; GR = grip strength; SDOC = Sarcopenia Definitions and Outcomes Consortium.
*Denotes putative sarcopenia variables identified in the SDOC primary analysis.