Table 4.
Sex-Stratified Comparison Between SDOC and EWGSOP2 Definitions of Probable Sarcopenia (Low Strength or Physical Performance) and Sarcopenia in Four Australian and New Zealand Cohorts by Prevalence and Agreement by Cohen’s Kappa
| Cohort | SDOC | EWGSOP2 | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Low Strength or Physical Performance | Sarcopenia | Low Strength or Physical Performance | Appendicular Lean Mass | Sarcopenia | ||||||
| Low GR W <20 kg M <35.5 kg |
Walking Speed <0.8 m/s | Low GR and Slow Walking Speed | Low GR W <16 kg M <27 kg |
Walking Speed ≤0.8 m/s | TUG ≥20 s |
ALM W <15 kg M <20 kg |
ALM/ht2 W <5.5 kg/m2 M <7 kg/m2 |
Low GR and ALM | Low GR and ALM/ht2 | |
| Cohort 1—Performance and strength cohort | ||||||||||
| Women | 295/1 121 (26.3) | 228/364 (62.6) | 135/363 (37.2) | 132/1 121 (11.8) | 230/364 (63.2) | 122/1 111 (11.0) | 230/1 151 (20.0) | 76/1 148 (6.6) | 60/1 111 (5.4) | 24/1 108 (2.2) |
| Men | 260/682 (38.1) | 110/675 (16.3) | 61/674 (9.1) | 52/582 (7.6) | 112/675 (16.6) | 46/678 (6.8) | 54/680 (7.9) | 61/680 (9.0) | 18/679 (2.7) | 16/679 (2.4) |
| Cohort 2—performance cohort | ||||||||||
| Women | — | 314/995 (31.6) | — | — | 315/995 (31.7) | 8/984 (0.8%) | 104/312 (33.3) | 52/312 (16.7) | — | — |
| Men | — | 149/461 (32.3) | — | — | 149/461 (32.3) | 0/453 (0.0%) | 16/172 (9.3) | 17/172 (9.9) | — | — |
| Cohort 3—strength cohort | ||||||||||
| Women | 887/2 440 (36.4) | — | — | 704/2 440 (28.9) | — | 1/169 (0.6) | 208/854 (24.4) | 66/852 (7.7) | 34/840 (4.0) | 13/840 (1.5) |
| Men | 881/2 045 (43.1) | — | — | 608/2 045 (29.7) | — | — | 55/737 (7.5) | 42/737 (5.7) | 13/729 (1.8) | 7/729 (1.0) |
| Cohort 4—Timed Up and Go cohort | ||||||||||
| Women | — | — | — | — | — | 0/49 (0.0) | 52/134 (38.8) | 21/134 (15.7) | — | — |
| Men | — | — | — | — | — | 0/16 (0.0) | 9/49 (18.4) | 6/49 (12.2) | — | — |
Notes: ALM = appendicular lean mass; EWGSOP2 = revised European Working Group for Sarcopenia in Older People; M = men; SDOC = Sarcopenia Definitions and Outcomes Consortium; W = women.
Cohen’s Kappa (95% CI; p value), proportionate agreement: Cohort 1 (women), SDOC vs EWGSOP2 (ALM) = 0.14 (0.07, 0.20; <.001), 40.1%; SDOC vs EWGSOP2 (ALM/ht2) = 0.07 (0.03, 0.12; .008), 34.2%; Cohort 1 (men), SDOC vs EWGSOP2 (ALM) = 0.21 (0.15, 0.25; <.001), 61.3%; SDOC vs EWGSOP2 (ALM/ht2) = 0.17 (0.12, 0.22; <.001), 59.9%; Cohort 2 (women), SDOC slow walking speed vs EWGSOP2 slow walking speed = 0.99 (0.99, 1.00; <.001), 99.9%; Cohort 2 (men), SDOC slow walking speed vs EWGSOP2 slow walking speed = 0.99 (0.97, 1.00; <.001), 99.3%; Cohort 3 (women), SDOC low GR vs EWGSOP2 (ALM) = 0.23 (0.19, 0.27; <.001), 64.9%; SDOC low GR vs EWGSOP2 (ALM/ht2) = 0.27 (0.23, 0.30; <.001), 73.9%; Cohort 3 (men), SDOC low GR vs EWGSOP2 (ALM) = 0.22 (0.18, 0.26; <.001), 69.7%; SDOC low GR vs EWGSOP2 (ALM/ht2) = 0.17 (0.14, 0.21; <.001), 68.0%.