Table 1.
Effects of piperacillin/tazobactam on serum creatinine and total protein levels with the Jaffe (Beckman) method and on serum creatinine levels using the enzyme (i-Stat) method compared with pooled serum samples with added saline⁎
| Sample | Jaffe creatinine (μmol/L) | Enzymatic creatinine (μmol/L) | Biuret total protein (g/L) |
|---|---|---|---|
| Pooled serum (PS) | 96 | 90 | 61 |
| 1/5 (saline/PS) | 65 | 61 | 48 |
| 1/5 (PipTaz/PS = 20 g/L) | 167 | 71 | 92 |
| 1/10 (saline/PS) | 85 | 76 | 54 |
| 1/10 (PipTaz/PS = 10 g/L) | 118 | 77 | 89 |
| 1/20 (saline/PS) | 92 | 85 | 58 |
| 1/20 (PipTaz/PS = 5 g/L) | 113 | 83 | 80 |
| 1/100 (PipTaz/PS = 1 g/L) | 95 | 79 | 59 |
⁎
PipTaz = piperacillin/tazobactam