Table 3.
Clinical outcomes at the latest follow-up*
| Outcomes | Values |
|---|---|
| Total number of patients | 73 |
| Follow-up (days), median (IQR) | 19.0 (15.0–27.0) |
| Clinical outcomes | |
| Status at Day 7 | |
| Alive in the hospital | 6 (8.2%) |
| Alive in the ICU | 61 (83.6%) |
| Death | 6 (8.2%) |
| Status at the latest follow-up | |
| Alive discharged home | 5 (6.8%) |
| Alive discharged to other facilities | 5 (6.8%) |
| Alive in the hospital | 13 (17.8%) |
| Alive in the ICU | 33 (45.2%) |
| Death | 17 (23.3%) |
| ICU mortality | 14 (19.2%) |
| Duration of mechanical ventilation (days), median (IQR) | 10.1 (8.0–14.3) |
| In survivors | 10.6 (8.0–15.8) |
| ICU length of stay (days), median (IQR) | 10.5 (8.0–15.0) |
| In survivors | 11.0 (8.0–16.0) |
| Hospital length of stay (days), median (IQR) | 16.0 (13.0–24.0) |
| In survivors | 18.0 (14.8–25.2) |
| Support at the latest follow-up | |
| ECMO | 5 (6.8%) |
| Tracheostomy | 20 (27.4%) |
| Prone positioning | 55/72 (76.4%) |
| Renal replacement therapy | 16 (21.9%) |
| Complications at the latest follow-up | |
| Bacterial pneumonia | 9 (12.3%) |
| Pneumothorax or pneumomediastinum | 7 (9.6%) |
| Stroke | 1 (1.4%) |
| Heart failure | 7 (9.6%) |
| Cardiac arrhythmia | 15 (20.5%) |
| Acute myocardial infarction | 1 (1.4%) |
| Myocarditis/pericarditis | 0 (0.0%) |
| Cardiac arrest | 6 (8.2%) |
| Bacteraemia | 27 (37.0%) |
| Other secondary infection | 3 (4.1%) |
| Disseminated intravascular coagulation | 2 (2.7%) |
| Transfusion of > 2 units of red blood cells | 25 (34.2%) |
| Rhabdomyolysis | 2 (2.7%) |
| Acute kidney injury | 55 (75.3%) |
| Stage 1 | 23/55 (41.8%) |
| Stage 2 | 15/55 (27.3%) |
| Stage 3 | 17/55 (30.9%) |
| Minor gastrointestinal haemorrhage | 1 (1.4%) |
| Gastrointestinal perforation | 1 (1.4%) |
| Liver dysfunction | 16 (21.9%) |
| Hyperglycaemia | 14 (19.2%) |
| Acute thrombosis (other than pulmonary embolism) | 1 (1.4%) |
| Limb ischaemia | 2 (2.7%) |
| Pulmonary embolism | 4 (5.5%) |
| Minor (non-life threatening) bleeding | 7 (9.6%) |
| Fungal infection | 12 (16.4%) |
ECMO = extracorporeal membrane oxygenation; ICU = intensive care unit; IQR = interquartile range.
Latest follow-up at 1 April 2020. Percentages may not total 100 because of rounding.