Skip to main content
. 2020 Dec 1;22(4):344–354. doi: 10.51893/2020.4.OA7

Figure 2.

Figure 2

Levels of uACE2 in critically ill patients with AKI*

AKI = acute kidney injury. AKI– = AKI stage 0 or 1 at 12 h of urine collection. AKI+ = AKI stage 2 or 3 at 12 h of urine collection. ICU = intensive care unit. uACE2 = urinary angiotensin-converting enzyme type 2. uCr = urinary creatinine. * Panel A compares uACE2 activity in ICU patients with AKI stage 0 or 1 at 12 h of urine collection, ICU patients with AKI stage 2 or 3 at 12 h of urine collection and healthy volunteers, with P values shown for between-group differences. uACE2 activity was significantly higher in ICU patients without AKI stage 2 or 3 at 12 h of urine collection, compared with the other two groups. Panel B shows uACE2 levels based on AKI stages (no AKI, n = 55; AKI stage 1, n = 18; AKI stage 2, n = 30; AKI stage 3, n = 2), with the P value representing significance of the association between uACE2 activity with AKI stage. In both figures, the y-axis was log-transformed to improve readability, and individual data and boxplots (representing median values, interquartile ranges, minimum and maximum values) are shown.