Table 2.
Analysis of primary outcome and secondary renal outcomes for AKI– and AKI+ patients*
| AKI– (n = 73) | AKI+ (n = 32) | P | |
|---|---|---|---|
| Primary outcome (AKI stage 2 or 3 at 12 h) | |||
| AKI stage† | – | ||
| Stage 1 | 18 (25%) | 0 | |
| Stage 2 | 0 | 30 (94%) | |
| Stage 3 | 0 | 2 (6%) | |
| Renal function indices at 12 h | |||
| Serum creatinine (μmol/L) | 80.0 (64.0–102.2) | 109.0 (87.0–187.5) | < 0.01 |
| Urine output (mL/kg/h) | 0.9 (0.7–1.4) | 0.4 (0.3–0.5) | < 0.01 |
| AKI defining criterion† | – | ||
| Serum creatinine alone | – | 2 (6%) | |
| Urine output alone | – | 25 (78%) | |
| Combination of both | – | 5 (16%) | |
| Secondary renal outcomes | |||
| Renal replacement therapy | 3 (4%) | 4 (12%) | 0.20 |
| AKI stage 2 or 3 at 24 h | 4 (5%) | 17 (53%) | < 0.01 |
| AKI stage 2 or 3 at any time | 7 (10%) | 32 (100%) | < 0.01 |
| Time to highest AKI stage (h) | 2.2 (–4.9 to 59.2) | 12.1 (11.0–13.1) | 0.11 |
AKI = acute kidney injury. AKI– = AKI stage 0 or 1 at 12 h of urine collection. AKI+ = AKI stage 2 or 3 at 12 h of urine collection. KDIGO = Kidney Disease: Improving Global Outcomes.
*
Data are median (interquartile range) or count (percentage).
†
According to KDIGO guidelines.