Table 2.

Adjusted hospital mortality and sensitivity analyses for confirmed coronavirus disease 2019 (COVID-19) admissions with completed outcome

	Low-volume group	High-volume group	Adjusted OR (95% CI)	P
Primary outcome*
Median split by site volume	17/102 (17%)	14/130 (11%)	0.96 (0.35–2.63)	0.93
Sensitivity analyses*
Median split by ICU-bed hours	20/128 (16%)	11/104 (11%)	0.9 (0.32–2.54)	0.85
High-volume arbitrarily set to > 10 COVID-19 admissions	22/134 (16%)	9/98 (9%)	1.41 (0.47–4.27)	0.54
Site volume as a continuous variable	na	na	1.04 (0.98–1.1)	0.17
Site ICU-bed hours as a continuous variable (per 100 hours)	na	na	1.02 (0.99–1.04)	0.27
With sample limited to mechanical ventilation patients only†
Median split by site volume	14/62 (23%)	12/68 (18%)	0.91 (0.29–2.82)	0.87
Median split by ICU-bed hours	17/79 (22%)	9/51 (18%)	0.81 (0.25–2.62)	0.73
High-volume arbitrarily set to > 10 COVID-19 admissions	19/90 (21%)	7/40 (18%)	1.3 (0.36–4.69)	0.69
Site volume as a continuous variable	na	na	1.04 (0.95–1.13)	0.43
Site ICU-bed hours as a continuous variable (per 100 hours)	na	na	1.01 (0.97–1.05)	0.6

ICU =intensive care unit; na = not applicable; OR = odds ratio.

^*n = 196.

^†n = 130.