Table 1.
Baseline characteristics and rescue therapies
| Variables | Overall | Missing |
|---|---|---|
| Number of patients | 262 | |
| Age (years), median (IQR) | 44 (29–62) | |
| Sex, male | 202 (77.1 %) | |
| Body weight (kg), median (IQR) | 75 (68–85) | |
| GCS at hospital admission, median (IQR) | 3 (3–7) | 0.4 |
| Pupillary reactivity at hospital admission | 6.9 | |
| Both reactive | 159 (65.2%) | |
| One reactive | 40 (16.4%) | |
| Non-reactive | 45 (18.4%) | |
| Pre-hospital hypoxia (SpO2 < 90%) | 46 (19.3%) | 9.2 |
| Pre-hospital hypotension (SBP < 90 mmHg) | 41 (16.9%) | 7.3 |
| Mass lesion on first CT scan* | 180 (68.7%) | |
| Traumatic SAH on CT scan | 186 (71%) | |
| Marshall score, median (IQR) | 3 (2–5) | 14.9 |
| IMPACT score (lab model), median (IQR) | 25 (14–40) | 0.4 |
| APACHE II score, median (IQR) | 20 (15–26) | 1.1 |
| Injury Severity Score, median (IQR) | 30 (25–42) | 0.4 |
| Use of barbiturate† | 34 (13%) | |
| Surgery for clot evacuation† | 94 (36%) | 0.4 |
| Decompressive craniectomy† | 78 (29.8%) | |
| External ventricular drainage† | 84 (32.1%) |
APACHE = Acute Physiology and Chronic Health Evaluation; CT = computed tomography; GCS = Glasgow Coma Scale; IMPACT = International Mission for Prognosis and Analysis of Clinical Trials in Traumatic Brain Injury; IQR = interquartile range; SAH = subarachnoid haemorrhage; SBP = systolic blood pressure; SpO2 = peripheral oxygen saturation.
*
Mass lesion indicates the presence of subdural haemorrhage, extradural haemorrhage, and/or intracerebral haemorrhage.
†
At any time point.