Table 3.
Outcomes: overall and by sedative agent used in the first 24 hours after intensive care unit (ICU) admission
| Outcomes | Overall | Propofol only | Midazolam only | Propofol and midazolam | No sedation | P* | Missing |
|---|---|---|---|---|---|---|---|
| Number of patients | 262 | 93 (35.5%) | 67 (25.6%) | 18 (6.9%) | 84 (32.1%) | ||
| ICU mortality | 64 (24.4%) | 19 (20.4%) | 18 (26.9%) | 3 (16.7%) | 24 (28.6%) | 0.496 | |
| Hospital mortality | 73 (27.9%) | 21 (22.6%) | 20 (29.9%) | 3 (16.7%) | 29 (34.5%) | 0.221 | |
| ICU LOS (days), median (IQR) | 14 (8-20) | 13 (7-19) | 16 (9-24) | 17 (13-24) | 13 (7-21) | 0.048 | |
| Hospital LOS (days), median (IQR) | 21 (11-34) | 21 (14-34) | 21 (12-31) | 25 (18-36) | 18 (8-35) | 0.268 | |
| GOS-E at hospital discharge | 0.031 | 36.3 | |||||
| Favourable (5–8) | 64 (38.3%) | 18 (28.1%) | 25 (47.2%) | 3 (30%) | 18 (45%) | ||
| Unfavourable (2–4) | 62 (37.1%) | 34 (53.1%) | 13 (24.5%) | 5 (50%) | 10 (25%) | ||
| Deceased (1) | 41 (24.6%) | 12 (18.8%) | 15 (28.3%) | 2 (20%) | 12 (30%) |
GOS-E = Extended Glasgow Outcome Scale; IQR = interquartile range; LOS = length of stay.
*
Comparison of the four groups: χ2 test and Kruskal-Wallis test for categorical and continuous variables respectively.