Table 1.
Patient characteristics, overall and for the subgroup of patients with microbiological isolates*
| 5 May 2014–4 May 2016, 24-bed old ICU | 5 May 2016 – 4 May 2018, 32-bed new ICU | |
|---|---|---|
| Number of admissions | 4388 | 5482 |
| Number of occupied bed-days | 14734 | 17305 |
| Age (years), median (IQR) | ||
| Overall | 62.0 (43.9–73.5) | 61.0 (44.6–72.2) |
| Subgroup | 63.3 (47.6–73.5) | 60.9 (44.1–71.4) |
| Sex, female† | ||
| Overall | 1529 (34.9%) | 2017 (36.8%) |
| Subgroup | 281 (33.7%) | 330 (34.3%) |
| Hospital duration (days), median (IQR) | ||
| Overall | 10 (5.8–19) | 8.7 (3.8–17) |
| Subgroup | 17 (8.9–31) | 16 (8.9–29) |
| ICU duration (days), median (IQR) | ||
| Overall | 1.9 (1.0–3.8) | 1.8 (1.0–3.5) |
| Subgroup | 5.1 (2.5–9.7) | 4.7 (2.2–9.5) |
| Hospital-ICU lag (days), median (IQR) | ||
| Overall | 0.4 (0.2–1.6) | 0.3 (0.1–1.0) |
| Subgroup | 0.3 (0.2–1.2) | 0.3 (0.1–0.8) |
| Hospital-specimen lag (days), median (IQR) | ||
| Overall | na | na |
| Subgroup | 2.8 (0.9–7.2) | 2.4 (0.8–6.8) |
| ICU-specimen lag (days), median (IQR) | ||
| Overall | na | na |
| Subgroup | 1.7 (0.4–4.7) | 1.4 (0.3–4.4) |
| Medical not surgical‡ | ||
| Overall | 2727 (62.2%) | 3297 (60.2%) |
| Subgroup | 626 (75%) | 724 (75%) |
| APACHE III score, median (IQR) [range]§ | ||
| Overall | 56 (41–76) [0–190] | 54 (39–73) [3–195] |
| Subgroup | 71.5 (55–91) [13–170] | 68 (51–88) [12–169] |
| ANZROD score, median (IQR) [range]§ | ||
| Overall | 0.04 (0.01–0.17) [0–1.0] | 0.04 (0.01–0.16) [0–1.0] |
| Subgroup | 0.14 (0.05–0.34) [0.00–0.97] | 0.13 (0.04–0.32) [0.0–0.98] |
| Principal ICU diagnosis¶ | ||
| Cardiovascular | ||
| Overall | 1512 (34.5%) | 1618 (29.5%) |
| Subgroup | 168 (20.2%) | 174 (18.1%) |
| Trauma | ||
| Overall | 611 (13.9%) | 875 (16.0%) |
| Subgroup | 153 (18.4%) | 174 (25.0%) |
| Sepsis | ||
| Overall | 514 (11.7%) | 506 (9.2%) |
| Subgroup | 139 (16.7%) | 240 (15.6%) |
| Neurological | ||
| Overall | 479 (10.9%) | 568 (10.4%) |
| Subgroup | 150 (18.0%) | 137 (14.2%) |
| Respiratory | ||
| Overall | 400 (9.1%) | 562 (10.3%) |
| Subgroup | 90 (10.8%) | n (10.2%) |
| Metabolic/endocrine | ||
| Overall | 321 (7.3%) | 363 (6.6%) |
| Subgroup | 45 (5.4%) | 54 (5.6%) |
| Gastrointestinal | ||
| Overall | 256 (5.8%) | 266 (4.9%) |
| Subgroup | 49 (5.9%) | 45 (4.7%) |
| Renal/genitourinary | ||
| Overall | 123 (2.8%) | 133 (2.4%) |
| Subgroup | 19 (2.3%) | 14 (1.5%) |
| Oncological** | ||
| Overall | 90 (2.1%) | 447 (8.2%) |
| Subgroup | 11 (1.3%) | 30 (3.1%) |
| Musculoskeletal/skin | ||
| Overall | 35 (0.8%) | 46 (0.8%) |
| Subgroup | 5 (0.6%) | 6 (0.6%) |
| Other/not specified | ||
| Overall | 17 (0.4%) | 9 (0.2%) |
| Subgroup | 0 | 0 |
| Haematological** | ||
| Overall | 16 (0.4%) | 56 (1.0%) |
| Subgroup | 4 (0.5%) | 13 (1.4%) |
| Gynaecological | ||
| Overall | 14 (0.3%) | 29 (0.5%) |
| Subgroup | 0 | 1 (0.1%) |
ANZCIS CORE = Australian and New Zealand Intensive Care Society Centre for Outcome and Resource Evaluation. ANZROD = Australian and New Zealand Risk of Death. APACHE = Acute Physiology and Chronic Health Evaluation. ICU = intensive care unit. IQR = interquartile range. na = not applicable.
This table summarises data on 9870 ICU admissions for 8726 individual patients for the 2 years before and 2 years after relocation of the ICU. The data for the microbial subgroup represent the first observed ICU admission for each of the 1890 individuals who yielded at least one positive microbial isolate from any anatomical site. Up to 5% of data may be missing for some estimates.
Sex was not documented for one patient in the old ICU.
Admitting unit was not documented for one patient in the old ICU and three in the new ICU.
ICU severity of illness as measured by APACHE III scores and the ANZROD predictive tool.
Principal diagnosis for each ICU admission in accordance with the ANZCIS CORE Adult Patient Database data dictionary. Within the ANZICS CORE requirements, APACHE III diagnostic codes are allocated to each admission in the following mandatory hierarchy: (i) cardiac arrest, (ii) sepsis, (iii) trauma. If a cardiac arrest occurs before ICU admission, the diagnostic code of cardiac arrest must be selected. If the patient has sepsis and has not had a cardiac arrest and is not post-operative, a sepsis diagnostic code must be selected. If the patient has any element of trauma relating to admission, and they have not had a cardiac arrest and do not present as septic, then a trauma diagnostic code must be selected. This diagnosis hierarchy may obscure other reasons for patient admission.
Leukemia/lymphoma will appear under a haematology diagnostic code (unless cardiac arrest, sepsis or trauma is present on ICU admission). As there is no ANZICS CORE APACHE III oncological diagnostic category, this was generated for all patients with an APACHE subcode related to cancers or likely malignant neoplasms of the respiratory, gastrointestinal, neurological and renal systems. The codes used were: 1302.02, 1302.03, 1303.01, 1303.02, 1405.01, 1405.02, 1405.03, 1405.04, 1405.05, 1405.06, 1405.07, 1505.01, 1701.01, 1701.02, 1701.03, 1701.04, 1701.05, 312.01, 312.02, 312.03, 312.04, 312.05, 202.02, 202.03, 202.04, 202.05, 405.01. Excluded were two codes for likely benign neoplasms (1302.01, thoracotomy for benign tumour [eg, mediastinal chest wall mass or thymectomy]; 1505.02, transsphenoidal surgery). These oncological codes are also subordinate to the APACHE III diagnostic hierarchy of cardiac arrest, sepsis or trauma. Subgroup proportions were based on 1795 cases where an APACHE subgroup code was available in the first patient admission.