Table 4.
Organisms defined as hospital-acquired, comparing old and new ICUs, in descending order of isolate count from the old ICU
| Organism | Old ICU* |
New ICU† |
IRR (95% CI)¶ | P** | ||
|---|---|---|---|---|---|---|
| Isolate count | IR‡ | Isolate count | IR§ | |||
| Coagulase-negative staphylococci | 297 | 20.2 | 220 | 12.7 | 0.63 (0.53–0.75) | < 0.01 |
| Enterococcus species | 230 | 15.6 | 178 | 10.3 | 0.66 (0.54–0.80) | < 0.01 |
| Non-VRE | 72 | 4.89 | 76 | 4.39 | 0.90 (0.64–1.26) | 0.52 |
| VRE (including surveillance) | 158 | 10.7 | 102 | 5.89 | 0.34 (0.26–0.42) | < 0.01 |
| VRE (excluding surveillance) | 51 | 3.46 | 30 | 1.73 | 0.50 (0.31–0.80) | < 0.01 |
| Staphylococcus aureus | 100 | 6.79 | 124 | 7.17 | 1.06 (0.80–1.39) | 0.69 |
| Non-MRSA | 87 | 5.90 | 108 | 6.24 | 1.06 (0.79–1.41) | 0.70 |
| MRSA | 13 | 0.88 | 16 | 0.92 | 1.05 (0.47–2.37) | 0.91 |
| Pseudomonas aeruginosa | 57 | 3.87 | 65 | 3.76 | 0.97 (0.67–1.41) | 0.87 |
|
Streptococcus pneumoniae Other drug-resistant organisms |
10 | 0.68 | 7 | 0.40 | 0.60 (0.19–1.73) | 0.30 |
| ESBL-producing organisms | 14 | 0.95 | 24 | 1.39 | 1.46 (0.73–3.05) | 0.26 |
| CPE | 2 | 0.14 | 0 | 0.00 | 0.00 (0.00–4.53) | 0.21 |
CPE = carbapenemase-producing Enterobacterales. ESBL = extended spectrum beta-lactamase. ICU = intensive care unit. IR = incidence rate. IRR = incidence rate ratio. MRSA = methicillin-resistant S. aureus. OBD = occupied bed-days. VRE = vancomycin-resistant enterococci.
24-bed ICU used during the period 5 May 2014 to 4 May 2016.
32-bed ICU used during the period 5 May 2016 to 4 May 2018.
Incidence per 1000 OBD across 14734 OBD in the 2 years from 5 May 2014 to 4 May 2016.
Incidence per 1000 OBD across 17305 OBD in the 2 years from 5 May 2016 to 4 May 2018.
IRR of the new ICU compared with the old ICU.
Mid P values for tests of IR difference.