Table 1.

Characteristics of the hypothyroid women and healthy control subjects. Data are presented as ratios, n (%), mean ± s.d., or median (full range).

	Patients	Controls	Pa
n	45	18
Mild:overt hypothyroidism	22:23
Age (years)	47.4 ± 11.4	45.2 ± 13.1	0.51
Body mass index (kg/m2)	28.4 ± 6.0	29.4 ± 5.5	0.58
Smoking, n (%)
Yes	6 (13.3)	0	0.23
No	37 (82.2)	18 (100)	0.23
Unknown	2 (4.5)	0	0.23
TPOAb at diagnosis (kIU/L)	590 (2–13,000)b
Time between baseline and follow-up (days)	442 (183–1354)
LT4 dose at follow-up (µg/day)	114 (0–200)c

^aDifference between hypothyroid participants and control subjects; ^bThree patients were negative for TPOAb but positive for anti-thyroglobulin antibodies (>60 mIU/L); ^cOne participant, initially hypothyroid, regained euthyroidism spontaneously, and the LT4 treatment could be discontinued.

LT4, levothyroxine; TPOAb, thyroid peroxidase antibodies.