Table 3.

Multiple regression associations of baseline excretion of 8-oxoGuo and 8-oxodG with demographic characteristics and baseline thyroid function test in 45 hypothyroid women. TPOAb, BMI, and TSH were not normally distributed, and a logarithmic transformation was applied.

	8-oxoGuo (n = 45)			8-oxodG (n = 45)
	β coefficienta	P	R2	β coefficienta	P	R2
Variables included			0.230			0.057
Age	0.309	0.049		0.169	0.321
BMI	0.107	0.459		0.042	0.791
TPOAb	0.021	0.899		0.202	0.276
TSH	−0.382	0.019		−0.217	0.215
Variables included			0.331			0.164
Age	0.277	0.055		0.155	0.328
BMI	0.157	0.252		0.101	0.505
TPOAb	0.063	0.680		0.276	0.112
FT4	0.525	<0.001		0.429	0.012
By stepwise multiple regression			0.219
Age	0.297	0.035
TSH	−0.348	0.015
By stepwise multiple regression
FT4	0.491	<0.001	0.241	0.310	0.038	0.096

^aStandardized coefficient.

8-oxoGuo, 8-oxo-7,8-dihydroguanosine; 8-oxodG, 8-oxo-7,8dihydro-2′-deoxyguanosine; BMI, body mass index; TSH, thyrotropin; FT4, free thyroxine; TPOAb, thyroid peroxidase antibodies.