Table 3.

Odds ratios regarding association between biomarkers and recurrence of differentiated thyroid cancer.

	Univariable		Multivariable		Multivariable
	OR (95% CI)	P	OR (95% CI)	P	OR (95% CI)	P
Thyroglobulin (>0.07 vs ≤0.07 ng/mL)	3.91 (1.15–13.29)	0.029	3.71 (1.02–13.42)	0.046	4.79 (1.31–17.52)	0.018
Thyroid-stimulating hormone (>0.24 vs ≤0.24 mIU/mL)	0.42 (0.11–1.62)	0.205
Neutrophil elastase (>64.0 vs ≤64.0 ng/mL)	7.65 (1.94–30.12)	0.004	7.37 (1.83–29.78)	0.005
Histone–DNA complex (>187.0 vs ≤187.0 AU)	4.00 (1.18–13.61)	0.026			4.96 (1.35–18.26)	0.016
Cell-free dsDNA (>79.0 vs ≤79.0 ng/mL)	6.04 (0.75–48.56)	0.091
Activated factor XII (>36.7 vs ≤36.7 mg/mL)	2.06 (0.62–6.82)	0.239
Endogenous thrombin potential (>1417.6 vs ≤1417.6 nM · min)	4.92 (0.61–39.65)	0.134

Multivariable logistic regression analyses were performed using statistically significant biomarkers in univariable analyses and collinearity between histone–DNA complex and neutrophil elastase was considered.

OR, odds ratio; CI, confidence interval; ds, double-stranded.