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. 2023 Nov 8;12(12):e230084. doi: 10.1530/EC-23-0084

Table 2.

Correlations between salivary androgens and self-reported pubertal development in boys. Data are presented as Spearman correlation coefficient.

Pubertal measure Testosterone A4 17-OHP 11-OHA4 11-KT DHEA
Collected at any time
n 148 148 144 145 145 155
Individual PDS components
 Axillary hair 0.52b 0.44b 0.34b 0.24b 0.35b 0.11
 Growth 0.32b 0.23b 0.21a 0.12 0.13 0.07
 Facial hair 0.56b 0.42b 0.36b 0.1 0.21b 0.1
 Pubic hair 0.39b 0.34b 0.22b 0.17a 0.29b −0.02
 Skin changes 0.18a 0.18a 0.02 0.05 0.15 0.07
 Voice changes 0.57b 0.46b 0.42b 0.25b 0.36b 0.24b
Composite PDS score 0.64b 0.51b 0.39b 0.23b 0.36b 0.13
PDS-derived pubertal categories 0.63b 0.50b 0.45b 0.19a 0.36b 0.15a
Before 11:00 h
n 58 58 58 56 57 62
Individual PDS components
 Axillary hair 0.53b 0.37b 0.39b 0.25 0.40b 0.08
 Growth 0.37b 0.24 0.28b −0.01 0.06 0.04
 Facial hair 0.63b 0.40b 0.46b 0.19 0.28a 0.07
 Pubic hair 0.53b 0.44b 0.42b 0.25 0.40b 0.02
 Skin changes 0.26a 0.29a 0.14 0.06 0.09 0.03
 Voice changes 0.67b 0.44b 0.50b 0.32a 0.51b 0.34b
Composite PDS score 0.75b 0.53b 0.57b 0.27a 0.45b 0.14
PDS-derived pubertal categories 0.69b 0.46b 0.57b 0.24a 0.42b 0.25b
After 11:00 h
n 85 85 81 84 83 88
Individual PDS components
 Axillary hair 0.52b 0.46b 0.29b 0.19 0.23a 0.17
 Growth 0.32b 0.22a 0.2 0.14 0.11 0.08
 Facial hair 0.49b 0.42b 0.26a 0.01 0.13 0.15
 Pubic hair 0.30b 0.30b 0.12 0.13 0.2 0.02
 Skin changes 0.16 0.09 −0.04 −0.05 0.05 0.12
 Voice changes 0.48b 0.41b 0.34b 0.14 0.2 0.14
Composite PDS score 0.57b 0.45b 0.29b 0.11 0.19 0.16
PDS-derived pubertal categories 0.58b 0.52b 0.39b 0.14 0.23b 0.12

a and b indicate statistically significant correlation coefficients where P < 0.05 and P < 0.01, respectively. Composite PDS scores were the mean of all six pubertal domain scores. The PDS-derived pubertal category in boys are derived from the sum of voice change, facial hair growth and body hair growth category from PDS self-report: prepubertal: 3, early pubertal: 4–5 (no 3-point responses), midpubertal: 6–8 (no 4-point responses), late pubertal: 9–11 and post pubertal: 12. In girls, the puberty category scores used body hair growth, breast development and menarche status as follows: prepubertal: 2 and no menarche, early pubertal: 3 and no menarche, midpubertal: >3 and no menarche, late pubertal <7 and menarche and post pubertal: 8 and menarche. Body hair growth in the present study was derived from the average scores between axillary hair and pubic hair development category in PDS self-report, rounded to the nearest integer.

11-OHA4, 11β-hydroxyandrostenedione; 17-OHP, 17-hydroxyprogesterone; A4, androstenedione; DHEA, dehydroepiandrosterone; PDS, Pubertal Development Scale.