Table 2.
Correlations between salivary androgens and self-reported pubertal development in boys. Data are presented as Spearman correlation coefficient.
| Pubertal measure | Testosterone | A4 | 17-OHP | 11-OHA4 | 11-KT | DHEA |
|---|---|---|---|---|---|---|
| Collected at any time | ||||||
| n | 148 | 148 | 144 | 145 | 145 | 155 |
| Individual PDS components | ||||||
| Axillary hair | 0.52b | 0.44b | 0.34b | 0.24b | 0.35b | 0.11 |
| Growth | 0.32b | 0.23b | 0.21a | 0.12 | 0.13 | 0.07 |
| Facial hair | 0.56b | 0.42b | 0.36b | 0.1 | 0.21b | 0.1 |
| Pubic hair | 0.39b | 0.34b | 0.22b | 0.17a | 0.29b | −0.02 |
| Skin changes | 0.18a | 0.18a | 0.02 | 0.05 | 0.15 | 0.07 |
| Voice changes | 0.57b | 0.46b | 0.42b | 0.25b | 0.36b | 0.24b |
| Composite PDS score | 0.64b | 0.51b | 0.39b | 0.23b | 0.36b | 0.13 |
| PDS-derived pubertal categories | 0.63b | 0.50b | 0.45b | 0.19a | 0.36b | 0.15a |
| Before 11:00 h | ||||||
| n | 58 | 58 | 58 | 56 | 57 | 62 |
| Individual PDS components | ||||||
| Axillary hair | 0.53b | 0.37b | 0.39b | 0.25 | 0.40b | 0.08 |
| Growth | 0.37b | 0.24 | 0.28b | −0.01 | 0.06 | 0.04 |
| Facial hair | 0.63b | 0.40b | 0.46b | 0.19 | 0.28a | 0.07 |
| Pubic hair | 0.53b | 0.44b | 0.42b | 0.25 | 0.40b | 0.02 |
| Skin changes | 0.26a | 0.29a | 0.14 | 0.06 | 0.09 | 0.03 |
| Voice changes | 0.67b | 0.44b | 0.50b | 0.32a | 0.51b | 0.34b |
| Composite PDS score | 0.75b | 0.53b | 0.57b | 0.27a | 0.45b | 0.14 |
| PDS-derived pubertal categories | 0.69b | 0.46b | 0.57b | 0.24a | 0.42b | 0.25b |
| After 11:00 h | ||||||
| n | 85 | 85 | 81 | 84 | 83 | 88 |
| Individual PDS components | ||||||
| Axillary hair | 0.52b | 0.46b | 0.29b | 0.19 | 0.23a | 0.17 |
| Growth | 0.32b | 0.22a | 0.2 | 0.14 | 0.11 | 0.08 |
| Facial hair | 0.49b | 0.42b | 0.26a | 0.01 | 0.13 | 0.15 |
| Pubic hair | 0.30b | 0.30b | 0.12 | 0.13 | 0.2 | 0.02 |
| Skin changes | 0.16 | 0.09 | −0.04 | −0.05 | 0.05 | 0.12 |
| Voice changes | 0.48b | 0.41b | 0.34b | 0.14 | 0.2 | 0.14 |
| Composite PDS score | 0.57b | 0.45b | 0.29b | 0.11 | 0.19 | 0.16 |
| PDS-derived pubertal categories | 0.58b | 0.52b | 0.39b | 0.14 | 0.23b | 0.12 |
a and b indicate statistically significant correlation coefficients where P < 0.05 and P < 0.01, respectively. Composite PDS scores were the mean of all six pubertal domain scores. The PDS-derived pubertal category in boys are derived from the sum of voice change, facial hair growth and body hair growth category from PDS self-report: prepubertal: 3, early pubertal: 4–5 (no 3-point responses), midpubertal: 6–8 (no 4-point responses), late pubertal: 9–11 and post pubertal: 12. In girls, the puberty category scores used body hair growth, breast development and menarche status as follows: prepubertal: 2 and no menarche, early pubertal: 3 and no menarche, midpubertal: >3 and no menarche, late pubertal <7 and menarche and post pubertal: 8 and menarche. Body hair growth in the present study was derived from the average scores between axillary hair and pubic hair development category in PDS self-report, rounded to the nearest integer.
11-OHA4, 11β-hydroxyandrostenedione; 17-OHP, 17-hydroxyprogesterone; A4, androstenedione; DHEA, dehydroepiandrosterone; PDS, Pubertal Development Scale.
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