. 2023 Nov 7;18(1):45–53. doi: 10.22074/IJFS.2023.1972296.1391

Table 2.

Ovarian morphological parameters, lipid and hormonal profile, and CRP of the experimental groups


Groups	Control	Letrozole	HFD	Letrozole+HFD

Ovary weight (Kg)	0.15 ± 0.02^a	0.27 ± 0.05^b	0.16 ± 0.04^a	0.25 ± 0.02^b
Preantral follicle	4.50 ± 1.05^a	9.50 ± 1.05^b	5.17 ± 0.98^a	14.00 ± 2.00^b
Antral follicle	3.00 ± 0.63^a	0.67 ± 0.52^b	3.00 ± 1.10^a	0.50 ± 0.55^b
Corpus luteum	4.17 ± 1.17^a	0.00 ± 0.00^b	1.33 ± 0.52^c	0.00 ± 0.00^b
Atretic follicles	0.83 ± 0.75^a	6.83 ± 1.17^b	2.17 ± 0.75^c	11.67 ± 1.63^d
Cystic follicles	0.50 ± 0.55^a	5.67 ± 1.033^b	3.33 ± 1.03^c	11.83 ± 1.06^d
Thickness of follicle wall (µm)	61.5 ± 7.31^a	121.83 ± 7.65^b	68.00 ± 3.63^a	135.83 ± 14.80^b
Oestrogens (pg/ml)	13.5 ± 3.08^a	4.67 ± 1.86^b	15.17 ± 4.58^a	5.50 ± 2.07^b
Testosterone (pg/ml)	0.19 ± 0.04^a	0.33 ± 0.05^b	0.19 ± 0.04^a	0.46 ± 0.05^c
Progesterone (ng/ml)	53.33 ±7.20^a	23.50 ± 6.57^b	54.33 ± 8.94^a	22.33 ± 5.47^b
TC (mmol/ml)	2.28 ± 0.35^a	2.95 ± 0.32^b	3.27 ± 0.27^b	3.89 ± 0.25^c
HDL (mmol/ml)	1.18 ± 0.19	1.03 ± 0.35	1.10 ± 0.34	1.05 ± 0.50
LDL (mmol/ml)	0.30 ± 0.04^a	0.43 ± 0.030^b	0.44 ± 0.03^b	0.50 ± 0.03^c
CRP (pg/ml)	14.02 ± 1.28^a	21.68 ± 1.03^b	17.35 ± 0.82^c	30.36 ± 1.44^d
HOMA-IR	5.09 ± 0.17	7.85 ± 0.40	12.48 ± 1.28	14.64 ± 1.17
BGL at 0 minute	5.93 ± 0.26	6.77 ± 0.25	7.43 ± 0.17	7.82 ± 0.12
BGL at 60 minutes	6.93 ± 0.25	8.22 ± 0.24	9.37 ± 0.25	10.92 ± 0.21
BGL at 120 minutes	6.13 ± 0.26	7.27 ± 0.25	8.23 ± 0.2	8.82 ± 0.12

Values are presented as mean ± SD. One-way ANOVA was performed for data analysis. A P<0.05 indicates statistical significance. Different letters are used to indicate significant differences within the same row. HFD; High-fat diet, HOMA-IR; Homeostasis model assessment of insulin resistance, TC; Total cholesterol, LDL; Low-density lipoprotein, HDL; Highdensity lipoprotein, BGL; Blood glucose levels, and CRP; C-reactive protein.