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Recovery and matrix effect of voriconazole in human plasma.
| Analyte | Nominal concentration (mg/L) | Recovery (%) |
IS normalized matrix factor (%) |
||
|---|---|---|---|---|---|
| Mean | RSD | Mean | RSD | ||
| Voriconazole | 0.2 | 100.5 ± 2.8 | 2.7 | 100.6 ± 5.0 | 5.0 |
| 1.0 | 102.6 ± 7.0 | 6.8 | |||
| 8.0 | 109.9 ± 2.2 | 2.0 | 92.9 ± 4.7 | 5.1 | |
| Voriconazole-d3 | 0.02 | 111.6 ± 6.4 | 5.8 | ||
RSD, relative standard deviations; SD, standard deviation.
