Table 5.
Time Intervals Between Clinical Genetic Tests and Reanalysis of All 144 VUSs That Were Reanalyzed (y)
| CMD (N = 44) | DD (N = 14) | EDMD (N = 13) | LGMD (N = 73) | Total (N = 144) | |
| Intervals | |||||
| Mean (SD) | 8.22 (1.99) | 7.00 (0) | 7.14 (1.21) | 8.31 (2.18) | 8.11 (2.00) |
| Median [Min, Max] | 8.00 [6.00, 13.0] | 7.00 [7.00, 7.00] | 7.00 [6.00, 9.00] | 7.50 [6.00, 14.0] | 7.00 [6.00, 14.0] |
| Missing | 17 (38.6%) | 11 (78.6%) | 6 (46.2%) | 37 (50.7%) | 71 (49.3%) |
| ACMG classification, n (%) | |||||
| Benign | 11 (25.0) | 6 (42.9) | 1 (7.7) | 5 (6.8) | 23 (16.0) |
| Likely benign | 3 (6.8) | 1 (7.1) | 1 (7.7) | 9 (12.3) | 14 (9.7) |
| Likely pathogenic | 5 (11.4) | 1 (7.1) | 0 (0) | 4 (5.5) | 10 (6.9) |
| Pathogenic | 4 (9.1) | 2 (14.3) | 0 (0) | 7 (9.6) | 13 (9.0) |
| VUS | 21 (47.7) | 4 (28.6) | 11 (84.6) | 48 (65.8) | 84 (58.3) |
The date used for reanalysis was December 13, 2022, the date when the VUS analysis was completed.